摘要
目的 :分析儿童呼吸道苛养菌的感染率及常用抗生素的耐药状况。方法 :采用儿童呼吸道 2 0 5 0份咽拭子及痰标本进行苛养菌分离培养与鉴定 ,并对其中 6 17株苛养菌做了药敏试验。结果 :显示 2 75株肺炎链球菌 ,耐药率较高的有红霉素81.1%、苯唑西林 76 .9%、复方磺胺甲口恶唑 76 .9%、四环素 6 5 .4 % ;10 4株流感嗜血杆菌、184株副流感嗜血杆菌、5 4株卡他莫拉菌对氨苄西林耐药率分别为 17.6 %、2 8.9%、6 4 .9% ,对亚胺培南 /西司他丁耐药率分别为 16 .4 %、16 .5 %、0 ,同时复方磺胺甲口恶唑的耐药率也分别高达 5 6 .7%、5 6 .7%、6 4 .9%。结论 :提示苛养菌在儿童呼吸道感染中占有重要的地位 ,及时掌握这类细菌的耐药动态 ,对合理使用抗生素、延缓耐药株的产生有极其重要的临床意义。
Objective:To analyse the infection rate and antibiotic susceptibility of respiratory tract fastidious bacteria in children. Method: The fastidious bacteria were isolated and identified which came from the pharynx-swabs and sputum specimen.2050 in total.of children′s repiratory tracts.Furthermore,the drug sensitirity tests were done on 617 strains of them.Results: The resistance rates of streptococcus Pneumoniae(275 strains) to erythromycin,oxacillin,SMZ-co and tetracycline were 81.1%,76.9%,76.9%,65.4%,respectively.The resistance rates of H influenzae(104 strains),H parainfluenzae(184 strains),M catarrhalis(54 strains) to ampicillin were 17.6%,28.9%,64.9%,respectively;to imipenem/cilastatin were 16.4%,16.5%,0;respectively;to SMZ-TMP were 56.7%,56.7%,64.9%,respectively; Conclusion: Fastidious bacteria possess a very important position in children′s respiratory tract infection.In order to use antibiotics reasonably and postpone the drug resistance,it is necessary to control the development of drug resistance of fastidious bacteria.This is important to the clinical use of antibiotics.
出处
《重庆医科大学学报》
CAS
CSCD
2003年第2期166-168,共3页
Journal of Chongqing Medical University
关键词
儿童
呼吸道
苛养菌
体外药敏试验
Children
Respiratory tract
Fastidious bacteria
Drug sensitivitg test
