摘要
从肺癌病人胸水和小鼠Hepatoma腹水中提取抑癌因子,分别作用于人羊膜上皮细胞、人喉上皮癌细胞、小鼠Hepatoma细胞、小鼠Sarcoma180细胞。实验证明,两种不同来源的抑癌因子对人羊膜上皮细胞影响极小,对三种癌细胞都有强烈的杀伤作用。这种专一杀伤癌细胞的特点可能在理论上和实用上有重要意义。
Cancer suppressive factors(CSFs) were isolated from hydrothorax of human lung cancer and ascites of mouse hepatoma. The two CSFs act on the cell lines of human amnion epithelium cells(FL), human larynx(Hep-2), mouse hepatoma and sarcoma 180. Our results have shown that the two CSFs of the human and mouse have no suppressive effects on human amnion epithelium cells(FL) which are proliferative cells, but have significant killing effects on the above-mentioned three cancer cell lines. The two CSFs killing effects were non-specific on the cancer's species and cell lines. The Killing specificity of the two CSFs for some cancer cells probably play an important role in future cancer research, both theoretically and practically.
出处
《贵阳医学院学报》
CAS
1992年第4期246-249,共4页
Journal of Guiyang Medical College
关键词
抑癌因子
上皮细胞癌
喉肿瘤
cancer-suppressive factor
human
amnion
epithelial cells
carcinoma
laryngeal neoplasms
liver neoplasms
lung neoplasms
sarcoma 180
