摘要
目的 探讨原发于胃肠道的恶性淋巴瘤 (PrimaryGastrointestinalMalignantLymphomaPGIML)治疗方式与疗效的关系。方法 回顾性分析我院 1981年 5月～ 1997年 5月治疗的 5 2例PGIML的资料 ,将其分为单纯手术 (单术 )、手术 +化疗 (术化 )及手术 +放疗 +化疗 (综合 )三个组 ,以kaplan Meier方法分别统计其 1、3、5年生存率 ,Logrank作显著性检验。 结果 单术、术化及综合组实际 5年生存率分别为 2 0 .0 %、6 0 .8%及 78.5 % ,与单术相比有显著性意义 (P <0 .0 5 ) ,尤以综合组的疗效最好。说明在PGIML治疗中 ,放疗是一种有效的手段。结论 PGIML治疗宜采用手术配合放、化疗的综合治疗。
Objective To evaluate the relationship between therapeutic methods and effects on primary gastrointestinal malignant lymphoma (PGIML). Methods From May 1981 to May 1997, fifty-two PGIML patients who were divided into three groups: operation alone (OA), surgery combined with chemotherapy (SC). and surgery combined radiotherapy and chemotherapy (SRC). These cases were analyzed retrospectively. The 1-3 and 5-year survival rates were statistically calculated by Kaplan Meier method and multiple factor Log-rank test. Results The 5year survival rates of OA. SC and SRC were 20.0%?60.8% and 78.5% respectively. There were significant differences comparing with OA. Especially, SCR group was more significant. The optimal effective treatment was SCR group. It shows that radiotherapy is one of effective treatment methods for PGIML. Conclusion Surgery combined with radiotherapy and chemotherapy is a suitable method for the treatment of PGIML.
出处
《肿瘤》
CAS
CSCD
北大核心
2003年第2期147-150,共4页
Tumor
关键词
原发性胃肠道淋巴瘤
手术
放疗
化疗
Primary gastrointestinal lymphoma
Surgery
Radiotherapy
Chemotherapy
