摘要
目的 探讨胃肠道原发性淋巴瘤的临床病理特征。方法 按 WHO (2 0 0 0年 )诊断标准 ,对 4 6例胃肠道原发淋巴瘤进行临床、病理组织形态观察、免疫组织化学标记 ,并结合文献复习。结果 4 6例胃肠道原发淋巴瘤 ,男∶女 =1.8∶ 1,发病年龄 4～ 77岁 ,以消化道症状和腹部包块为主诉。好发部位 :胃 15例 ,小肠 2 3例 ,大肠 8例。组织学类型 :4 6例均为非霍奇金淋巴瘤 (NHL) ,B细胞性淋巴瘤 38例占 82 .6 % ,其中粘膜相关淋巴组织型边缘区 B细胞淋巴瘤 (MAL T- type) 19例 ,弥漫性大 B细胞性淋巴瘤 (DL BCL ) 15例 ,滤泡性淋巴瘤 (FL ) 1例 ,套细胞淋巴瘤(MCL) 1例 ,Burkitt样淋巴瘤 2例 ,T细胞淋巴瘤 8例占 17.4 %。不同组织学类型的淋巴瘤其免疫表型和临床表现不同。结论 胃肠道原发性淋巴瘤具有其独特的临床病理特征 。
Objective To study the clinical and pathological features of primary gastrointestinal lymphoma (PGIL).Methods According to WHO classification of lymphoma(2000),46 cases of GIPL wereo bserved by the clinical and morphologic pattern and immunohistochemical stain.Results 46 cases of PGIL,the male were more than the female(1 8∶1),ages of illness were 4～77 year,most of the cases had the abdominal mass and gastrointestinal tract symptom.The small intestine was the most common site involved,followed by stomach,colon and rectum.Histological classification:46 cases of PGIL were all NHL,38 of them were B cell lymphoma,amounting to 82 6%(MALT type 19 cases,DLBCL 15 cases,FL 1 case,MCL 1 case,Burkitt like 2 cases);8 cases were T cell lymphoma,amounting to 17 4%.Different types of PIGL differed in the immunophenotype and clinical feature.Conclusion PGIL comprises a group of distinctive clinicopathological tumours. Histological classification and clinical term were important guidance for treatment.
出处
《福建医药杂志》
CAS
2002年第6期125-127,共3页
Fujian Medical Journal
关键词
胃肠道
原发性淋巴瘤
组织学类型
免疫组化
Gastrointestinal
Primary lymphoma
Histological classification
Immunohistochemistry
