摘要
目的 :了解广西地区儿童铅中毒状况 ,研究铅对婴儿神经发育的影响。方法 :选择 10 2 0名婴儿 ,以脐血铅作为铅暴露示标 ,3月龄时在贝利 (Bayley)婴儿发育表上以精神发育指数 (MDI)和心理运动发育指数 (PDI)为效应示标。结果 :血铅≥ 0 .4 8μm ol/ L 的婴儿其 MDI和 PDI明显落后于相对低铅组 ,随着分界线的下移 ,两组间 MDI和 PDI差别渐趋缩小 ,当分界线为0 .2 4 μmol/ L 时 ,高、低铅组 MDI和 PDI已不存在统计学差异。结论 :当血铅≥ 0 .4 8μm ol/ L 时 ,婴儿神经行为发育即可受到不利影响。
Objective: 1 020 babies were selected and their umbilical blood lead level were determined as a marker to reflect their exposure so as to study the diagnostic criteria for lead poisoning in young children Methods: Mental development index (MDI) and psychomotor development index (PDI) of three month babies in Bayley scales of infant development were used as effective indicators to study effects of lead on their development Results: It is indicated that both MDI and PDI in infants with blood lead level of greater than or equal to 0 48 μmol/L were obviously lower than those with less than 0 48 μmol/L All the children were divided into two groups (high blood lead and low blood lead) according to the cut off values for blood lead level of 0 72, 0 48, and 0 24 μmol/L, respectively, and the difference in MDI and PDI between the two groups decreased gradually with the cut off value decreasing Conclusion: There was no difference in them between the two groups when the cut off point lowering down to 0 24 μmol/L
出处
《广西医科大学学报》
CAS
2002年第6期793-794,共2页
Journal of Guangxi Medical University
基金
广西科技发展基金 (桂科基 0 73 2 0 10 )
广西柳州市科技发展基金资助项目 (柳科基 980 42 8)
