摘要
目的探讨特发性阵发性与持续性心房颤动患者的血浆心钠素 (ANP)水平的变化及其原因。方法采用放射免疫分析法检测 2 1例特发性阵发性房颤患者房颤发作时 (A1 组 )和房颤终止后 7天 (A2 组 )及 2 8例特发性持续性房颤患者 (B组 )的血浆ANP水平 ,同时测定各组红细胞压积及血小板数 ,并与健康对照组 (C组 )进行比较。结果特发性阵发性房颤患者房颤发作时及特发性持续性房颤患者的血浆心钠素水平及红细胞压积均显著高于正常对照组 (P <0 .0 1) ,而A1 组的血浆心钠素水平和红细胞压积显著高于A2 组 (P <0 .0 1) ,但血小板各组间差异无显著性 (P >0 .0 5)。结论特发性阵发性及特发性持续性心房颤动患者均存在血液浓缩 。
Objective To study the changes of plasma atrial natriuretic peptice(ANP) and causes in patients with idiopathic paroxysmal and perpetual atrial fibrillation. Methods Radioimmunology analysis was used to measure plasma ANP levels and hematocrit(HCT) and blood platelet count(BPC) was performed in 21 patients with paroxysmal idiopathic atrial fibrillation during(auricular fibrillation,AF) and 7 days after reture to sinus rhythm and in 28 patients with perpetual idiopathic atrial fibrillation. Levels of ANP was compared with healthy subjects. Results HCT and ANP in the patients with perpetual idiopathic atrial fibrillation were significantly higher than that in control gorup(P<0.01), but HCT and ANP in the patients with paroxysmal idiopathic AF during AF as well as perpetual AF were higher than that of recovery of AF 7 days later and healthy subjects (P<0.01) . There was not significant difference in BPC between the patients with idiopathic AF and healthy subjects (P>0.05) . Conclusion The blood condensing occurs in the patients with idiopathic atrial fibrillation, which is related to the increase of ANP release.
出处
《中国综合临床》
北大核心
2003年第3期220-220,222,共2页
Clinical Medicine of China
