摘要
目的 观察藤黄酸对肿瘤细胞的诱导分化作用。方法 从增殖能力、细胞形态和功能变化 3个方面评价藤黄酸对肿瘤细胞的诱导分化作用。结果 藤黄酸可提高K 5 62细胞的Hb含量 ,降低B16细胞黑色素含量 ,抑制Bel 740 2细胞增殖并在形态上有趋向分化的改变。结论 实验显示藤黄酸有诱导肿瘤细胞分化的作用。
Objective To study the inducing differentiation effect of gambogic acid.Methods Inducing differentiation effect of gambogic acid were evaluated by proliferation,morphology and function of tumor cells.Results Hb content of K562 cell was increased,melanin content of B16 cell was decreased and proliferation of Bel 7402 cell was inhibited by gambogic acid.And Bel 7402 cell showed induce differentiation in morphology.Conclusion Gambogic acid has inducing differentiation effect on tumor cells.
出处
《实用癌症杂志》
2003年第1期9-10,共2页
The Practical Journal of Cancer
关键词
藤黄酸
肿瘤
细胞
诱导分化
Gambogic acid
Tumor
Cells
Inducing differentiation
