摘要
为探讨山东省中小学生麻疹爆发的原因 ,采用 1∶2配比的病例对照方法对中小学生麻疹疫苗 (MV)效力进行了研究 ,同时对近年来中小学生MV接种率进行了估算。结果显示 :中小学生MV效力为 74 % ,95 %可信区间为4 7%～ 88% ;小学生MV效力明显高于中学生 ,分别为 82 %和 6 8% ;1999～ 2 0 0 1年学龄儿童的估算接种率分别为75 4 %、75 6 %和 5 5 7%。较低的MV效力和接种率是计划免疫工作薄弱地区中小学生麻疹爆发的主要原因。
In order to discuss the reasons for measles outbreak in primary and junior middle school students in Shandong Province,we made a 1∶2 case-control study to estimate measles vaccine efficacy and also the measles vaccine coverage rate among school-age children in recent years.The results showed that measles vaccine efficacy among primary and junior middle school students in Shandong Province was 74%(95% confidence interval,47%～88%)and the estimated measles vaccine coverage rates among school children in 1999,2000 and 2001 were 75.4%?75.6% and 55.7% respectively.The main reasons for measles outbreak among school children in weak EPI area of our province were the low measles vaccine efficacy and the low measles vaccine coverage rate.
出处
《中国计划免疫》
2003年第1期13-15,共3页
Chinese Journal of Vaccines and Immunization
关键词
山东
中小学生
麻疹
爆发原因
病例对照研究
疫苗效力
Primary and junior middle school students
Measles outbreak
Vaccine efficacy
Case-control study
