摘要
本文建立了测定吸毒者尿中吗啡浓度的方法,样品经酸解、醚洗、碱化及溶剂提取后,用MSTFA衍生化,最后用GC/MS(SIM)法分析,以内标法定量。
A rapid sensitive method has been developed for the determination of the concentration of morphine in drug addicts' urine by using GC/MS combined with Selected Ion Monitoring (SIM) technique. The peak area ratio of morphine to dihydrocodeine(internal standard) is proportional to the concentration of morphine from 10 ng/mL to 1000 ng/mL. The recovery and detection limit are 96. 6±1. 8(n = 4) and 0. 5 ng. The method has been used to determine the concentration of drug addicts who were being treated in a hospital.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1992年第5期608-610,共3页
Chemical Journal of Chinese Universities
关键词
吗啡
吸毒者
GC/MS
Morphine, Drug addicts, Gas chromatography-mass spectrometry
