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侵袭性垂体腺瘤发生的分子病理机制 被引量:1

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摘要 目的 垂体腺瘤是颅内常见的单克隆性肿瘤 ,其生长缓慢 ,多为良性 ,但有相当一部分肿瘤可表现出侵袭性行为。侵袭性垂体腺瘤常引起一系列严重临床症状 ,致死率很高。在侵袭性垂体腺瘤的发生、发展中 ,某些基因起重要作用 ,如GSP ,MEN 1,P5 3,ras,Rb ,nm2 3基因等。人工合成的MMP 9抑制因子、溴麦角环肽、生长抑素、抗甲基化作用的药物可用于侵袭性垂体腺瘤的治疗。
出处 《临床军医杂志》 CAS 2003年第1期82-84,共3页 Clinical Journal of Medical Officers
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