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人脑垂体腺瘤遗传学研究的进展

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摘要 现代肿瘤学认为遗传物质的改变在垂体腺瘤的发生、发展过程中起着重要作用。目前研究认为7、8、12、X等染色体的获得可能参与其启动阶段,而11、13等染色体丢失可能与肿瘤发展及侵袭性生长密切相关。另外,Gsp、Ras等原癌基因突变,Rb、p53、MEN-l等抑癌基因灭活与垂体腺瘤发病关系较为密切。
作者 王清 惠国桢
出处 《国外医学(神经病学.神经外科学分册)》 2002年第5期398-401,共4页 Foreign Medical Sciences(Section On Neurology & Neurosurgery)
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