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阿尔茨海默病临床特征Logistic回归分析对照研究 被引量:1

The Clinic Characteristics of AD Patients and 105 Patients with Brain-infarction as Control Investigated by Logistic Regression
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摘要 目的 分析 77例阿尔茨海默病和 10 5例脑梗死患者的临床特征 ,寻找鉴别诊断依据。方法 用MMSE测定、CT检查等进行调查。结果 进入Logistic回归方程的有精神病病程、发作特点、高血压史等因素 ,显示AD者精神病程较长 ,以缓慢起病为主 ,MMSE总分较低 ,往往无高血压史 ,妄想、幻觉、记忆减退、兴奋多言及意识障碍出现频度明显不同于脑梗死组 (P <0 .0 5~ 0 .0 0 1)。结论 熟悉病程特点 ,测定认知功能水平 ,必要的CT或MRI检测 。 Objective To investigate the foundation of differential diagnosis through the analysis of the clinic characteristics of 77 AD patients and 105 patients with brain-infarction. Methods MMSE and CT were used. The course, attack feature and the history of hypertension were collected for the Logistic Regression. Results We found that the longer course, the slower attack, the lower MMSE, and without the history of hypertension were the features of AD. The onset frequency of delusion, hallucination, decline in memory, excitement, increased speech and loss of consciousness was significantly different to the brain-infarction. Conclusions The feature of the course of AD, the level of cognitive function and the monitor of CT or MRI are necessary approaches for differential diagnosis.
出处 《神经疾病与精神卫生》 2003年第1期21-23,共3页 Journal of Neuroscience and Mental Health
关键词 阿尔茨海默病 脑梗死 LOGISTIC回归分析 Alzheimer'disease Brain infarction Logistic Regression
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