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桑色素及其配合物与DNA作用的研究 被引量:20

Studies on the Interactions Between Morin and Its Cu(Ⅱ)-, Zn(Ⅱ)-Complexes with DNA
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摘要 The interactions of Morin and its Cu(Ⅱ)-, Zn(Ⅱ)-complexes with calf thymus DNA have been studied by using fluorimetric and electrochemical methods. Cu(Ⅱ)-, Zn(Ⅱ)-complexes have different spectra and electrochemical characteristics from that of Morin in the presence of DNA. The results suggest that Morin and its complexes can both bind to DNA, but the binding mode is different. The complexes bind to DNA mainly like EB by intercalation, while Morin binds in a non-intercalating mode. The interactions of Morin and its Cu(Ⅱ)-, Zn(Ⅱ)-complexes with calf thymus DNA have been studied by using fluorimetric and electrochemical methods. Cu(Ⅱ)-, Zn(Ⅱ)-complexes have different spectra and electrochemical characteristics from that of Morin in the presence of DNA. The results suggest that Morin and its complexes can both bind to DNA, but the binding mode is different. The complexes bind to DNA mainly like EB by intercalation, while Morin binds in a non-intercalating mode.
出处 《高等学校化学学报》 SCIE EI CAS CSCD 北大核心 2003年第2期249-251,共3页 Chemical Journal of Chinese Universities
基金 西北师范大学科技创新工程和西北师范大学青年自然科学基金资助
关键词 桑色素 配合物 DNA 作用方式 荧光 抗肿瘤活性 Morin Complex DNA Binding mode Fluorescence
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参考文献1

  • 1叶能胜 邹洪 朱若华 et al.Chemical Education(化学教育)[J],2000,11:1-4.

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