摘要
对近临界水介质中不同芳香醛化合物与酮类进行Claisen Schmidt缩合反应的研究表明 ,在没有外加任何催化剂的条件下 ,芳香醛与酮类可以顺利发生缩合反应得到α ,β 不饱和酮 ,近临界水在其中兼作溶剂和催化剂 .该方法避免了酸或碱催化剂的使用及随后繁杂的中和、分离步骤 ,克服了产生废弃盐等弊端 .通过对苯甲醛与苯乙酮在不同条件下的反应研究表明 ,温度 ,反应时间和初始水量对反应底物的转化率和不饱和酮的产率有较大的影响 .
The investigation of Claisen-Schmidt condensation of aromatic aldehydes with different ketones indicates that α,β-unsaturated ketones can be obtained without any catalyst in near-critical water. Near-critical water serves both as a reaction medium and as a catalyst. Neutralization of acid or base catalyst, separation treatment and deposal waste salts after reaction in the classical methods are avoided. The yields and conversions of the reaction were influenced by reaction time, temperature and initial water volume.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2003年第1期72-75,共4页
Chinese Journal of Organic Chemistry
基金
广东省自然科学基金 (No.990 749)资助项目
