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染色体畸变及微核估算事故受照者生物剂量的比较研究 被引量:10

COMPARISON OF ESTIMATION INDIVIDUAL BIOLOGICAL DOSE TO ACCIDENTAL RADIATION BY CHROMOSOME ABERRATIONS AND MICRONUCLEI
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摘要 用外周血淋巴细胞染色体畸变(双+环)和微核的剂量效应曲线估算了5例受^(60)Co γ线事故照射病人的生物剂量。结果表明,在照后早期,用上述两种方法估算的剂量与物理剂量基本一致。尤其对较均匀照射的3例(A、B和E)“双十环”剂量与物理剂量相当吻合,同时发现,用微核率估算的剂量偏高。本文对上述结果进行了讨论。 Biological doses of 5 cases exposed to ^(60)Co γ-ray were estimated bythe curves of relationships between radiation dose and chromosome aberations and mi-cronuclei of periphcral blood lymphocytes. The results indicated that biological doseestimated by 'dic. + r.' and micronuclei were quite approximate to the physical dose atearly phase of post irradiation. Specially, in 3 cases of uniform doses. the doses esti-mated by 'dic. + r.' were nearly identical to the physical dose. At the same time, itwas showed that dose estimated by micronuclei were higher than those of 'dic. + r.'doses.
出处 《辐射研究与辐射工艺学报》 CAS CSCD 北大核心 1992年第4期228-231,共4页 Journal of Radiation Research and Radiation Processing
关键词 染色体畸变 生物剂量 微核测试 ^(60)Co γ-ray Accidental radiation Chromosome aberrations Micronucleus Biological dose
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  • 1杨家宽,蔡荣妹,邵敏,刘德喜.人血淋巴细胞微核测定可以用作辐射生物体量计[J]辐射研究与辐射工艺学报,1988(03).
  • 2白玉书,张秀霞,关树荣.Co-γ-线照射离体人血诱发的淋巴细胞微核与剂量的关系[J]遗传,1982(03).

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