1[1]Polyak K,Lee MH,Erdjument-Bromage H,et al.Cloning of p27 kipl,a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals[J].Cell,1994,78:59～66.
2[2]Toyoshima H,Huntuter T.p27,a novel inhibitor of G1cyclin-cdk protein kinase activity,is related to p27[J].Cell,1994,78:67～72.
3[3]Fero ML,Randel E,Gurley KE,et al.The murine gene p27 kipl is haplo-insufficiet for turnour suppression[J].Nature,1998,396 (6707):177～180.
4[4]Anayama T,Furihata M,Ishikawa T,et al.Positive correlation between p27 kipl expression and progression of human esophageal squamous cell carcinoma[J].Int J Cancer,1998,79 (4):439～443.
5[5]Cheville JC,Lieyd RV,Sebo TJ,et al.Expression of p27kipl in prostatic adenocarcinoma[J].Mod Pathol,i998,11 (4):324～328.
6[6]Lioyd RV,Jin L,Qian X,et al.Aberrant p27 kipl expression in endocrine and other tumors[J ].Am J Pathol,1997,150(2):401～407.
7[7]Thomas GV,Szigeti K,Murphy M,et al.Down-regulation of p27 is associated with development of colorectal adenocarcinoma metastases[J].Am J Pathol,1998,153(3):681～687.
8Blasco MA,Lee HW,Hande MP,et al.Telomere shortening and tumor formation by mouse cells lacking telomerase RNA[].Cell.1997
9Clurman BE,Roberts JM.Cell cycle and cancer[].Journal of the National Cancer Institute.1995
3Kurki P, Ogata K, Tan EM. Monoclonal antibodies to proliterating cell nuclear antigen (PCNA/cyclin) as probes for proliferating cell by immunofluoressence microscopy and flow cytometry. J Immunol Methods, 1988,109:49～59.
4Vlach J, Hennecke S. Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27KIP1. EMBO J,1997,16(17) :5334.
5Chen J, Willingham T, Shuford M, et al. Tumor suppression and inhibition of aneuploid cell accumulation in human brain tumor cells by ectopic overexpression of the cyclin-dependent kinase inhibitor p27 KIP1. J Clin Invest, 1996,97(8) :1983～8.
6Shamma A,Doki Y,Shiozaki H,et al.Effect of cyclin D1 and associated proteins on proliferation of esophageal squamous cell carcinoma[J].Int J Oncol,1998,13(3):455-460.
7Kurki P,Ogata K,Tan EM.Monoclonal antibodies to proliferating cell nuclear antigen(PCNA/Cyclin) as probes for proliferating cells by immunofluressence microscopy and flow cytometry[J].J Immunol methods,1988,109(1):49-59.
