摘要
目的:观察比较脾气虚证模型、脾不统血证模型与单纯出血因素及卵巢摘除大鼠血浆、子宫PG的变化。方法:以放射免疫法检测上述模型大鼠血浆、子宫6-酮-前列腺素F_(1α)(6-K-PGF_(1α))和血栓素B_2(TXB_2)。结果:各种造模因素均导致血浆、子宫6-K-PGF_(1α)/TXB_2升高,机体表现为出血倾向。结论:6-K-PGF_(1α)/TXB_2比值升高可能是脾不统血证出血的机理之一。
Aim: To observe and compare the change of serum and uterus PG betvveen the modei of spleen - qi defi-ciency syndrome, spleen failing to be in charge of blood syndrome and simple hemorrhagic factors and ovariotomy rats. Method: Radio - immunity method was applied to measure the serum and uterus 6 - K - PGF1αand TKB2 of above - noted modei rats. Result: The above - mentioned induced - modei factors all can result in the increase of serum and uterus 6 -K - PGF1α/TXB2 and hemorrhagic tendency of rats. Conclusion: The ratio increase of 6 - K - PGF1α/TXB2 is likely to be one of important mechanisms of hemorrhage in ' spleen fails to be in charge of blood' syndrome.
出处
《中国医药学报》
CSCD
2002年第12期726-728,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
国家中医药管理局资助课题
高等学校博士基金
