摘要
目的:建立七子二仙胶囊的质量控制方法。方法:用薄层色谱法对七子二仙胶囊制剂中的淫羊藿、菟丝子、枸杞子、丹参进行定性鉴别,HPLC法测定淫羊藿苷的含量。结果:鉴别方法专属性好,测定淫羊藿苷的线性范围为1～300μg/mL,r=0.9996,最低检测浓度0.2μg/mL,平均加样回收率96.6％(n=5)。结论:方法专属性好,稳定,可用于七子二仙胶囊质量控制。
Objective: To develop effective methods for the quality control of Qizierxian capsule. Method: TLC was performed to identify Epimedium brevicornum Maxim, Cuscuta chinensis Lam, Curculigo orchioides and Salvia miltiorrhiza in Qizierxian capsule preparations . HPLC was used to determine the content of icariin. Results: The standard curve of icariin by HPLC was linear in the range of 1 - 300 μg/mL, r =0. 9996. The minimum determination consents was 0. 2 μg/mL, the average recovery of icariin was 96. 6% , (n = 5). Conclusion: The methods are simple, sensitive and accurate. These studies provide the scientific base for quality control of Qizierxian capsule.
出处
《广东药学院学报》
CAS
2002年第4期272-275,共4页
Academic Journal of Guangdong College of Pharmacy
