摘要
目的:探讨99mTc-甲氧基异丁基异腈(MIBI)显像鉴别乳腺肿块良恶性的临床价值。方法:对195例乳腺肿块行99mTc-MIBI显像检查。全部病例均手术治疗,与病理结果比较。结果:195例中,乳腺癌84例,显像阳性69例,假阴性主要为肿块较小的和恶性程度高的乳腺癌;良性病变111例,显像阴性102例,假阳性主要是血供丰富的大纤维腺瘤。该法对乳腺癌诊断的灵敏度为82.1％,特异性为92.0％,诊断正确率为89.2％。结论:99mTc-MIBI显像是临床鉴别乳房肿块良恶性的有效方法,具有简便、有效和无创的优点。
Purpose: To explore the clinical value of 99mTc-MIBI imaging in differentiating malignancies from benign breast masses. Methods: 195 patients underwent the examination for 99m Tc-MIBI. Comparative diagnosis was done by postoperative pathology in all cases. Results: 69 of the 84 cases of breast cancer were preoperatively diagnosed by 99mTc-MIBI, the causes of false-negative results were small size of the mass and the higher degree of malignancy. 102 of the 111 patients with benign lesions were scintimammographically negative, the cause of false-positive results was large fibroadenomas with surplus blood supply. The sensitivity was 82. 1%, specificity was 92.0%, and the diagnostic accuracy was 89.2%. Conclusions: 99mTc-MIBI examination is an effective, simple and noninvasive diagnostic method for primary breast cancer.
出处
《中国癌症杂志》
CAS
CSCD
2002年第6期551-552,共2页
China Oncology
关键词
乳腺肿瘤
放射性核素显像
异腈类
breast neoplasms
radionuclide imaging
isonitriles
