摘要
杯 [4 ]芳烃四丁醚经过对位硝化反应后在水合肼作用下被还原成氨基衍生物 ,并进一步与异硫氰酸苯酯反应得到单取代与 1,3 二取代的杯 [4 ]芳烃硫脲衍生物 ,总收率为 5 0 %.它们对系列阴离子的络合实验表明氢键的形成在络合过程中有重要作用 ,其中杯 [4 ]双硫脲衍生物 5b对H2 PO-4 显现出良好的选择性络合能力 .
The mono- and 1,3-disubstituted calix[4]-thiourea derivatives were synthesized by stepwise method with convenient procedure in total 50% yield. It was found that the hydrogen bond played an important role in complexation of these calix[4]arene derivatives with anions. Calix[4]-bis-thiourea derivative 5b shows high complexation capability with H2PO4- which indicates the size of H2PO4- matched the structure of the host compound.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2002年第12期1040-1043,共4页
Chinese Journal of Organic Chemistry
基金
福建青年科技人才创新专项资金 (No .2 0 0 1J0 2 5 )
福建省自然科学基金 (No.E0 0 10 0 18)资助项目
