4Li J, Yen C, Liaw D, et al. PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science, 1997, 275: 1943-1947.
5Wu RC,Li X,Schonthal AH. Transcriptional activation of p21/WAF1 by PTEN/MMAC1 tumor suppressor. Mol Cell Biochem,2000, 203: 59-71.
6Myers MP, Stolarov JP, Eng C, et al. P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase. Proc Natl Acad Sci U S A, 1997, 94: 9052-9057.
7Tian XX, Pang JC, To SS, et al. Restoration of wild-type PTEN expression leads to apoptosis, induces differentiation, and reduces telomerase activity in human glioma cells. J Neuropathol Exp Neurol,1999, 58: 472-479.
8Stambolic V, Suzuki A, dela Pompa JL, et al. Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN. Cell,1998, 95: 29-39.
9Li DM, Sun H. TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor β. Cancer Res,1997, 57: 2124-2129.
10Burger AM, Bibby MC, Double JA. Telomerase activity in normal and malignant mammalian tissues: feasibility of telomerase as a target for cancer chemotherapy. Br J Cancer, 1997,75: 516-522.
