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人端粒酶逆转录酶hTERT在肿瘤治疗研究中的进展 被引量：1

Progress of Human Telomerase Reverse Transcriptase hTERT in Remedial Study of Tumour
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摘要 人端粒酶逆转录酶 hTERT 是构成端粒酶的组分之一,是端粒酶活性的必需和限速成分,其水平决定细胞端粒酶的活性。抑制 hTERT可降低端粒酶的活性,从而抑制瘤细胞生长。目前对hTERT 的研究已成为端粒酶研究的热点问题,已发现hTERT蛋白表达在肿瘤诊断中有重要意义,并制备了hTERT 抗体及应用核酶技术等来抑制hTERT蛋白的表达,抑制端粒酶活性,从而抑制肿瘤的生长。笔者综述了近年来关于hTERT在肿瘤治疗方面的进展。
作者 陈立梅 杜瑞红
机构地区 北华大学医学院细胞生物学教研室
出处 《深圳中西医结合杂志》 2004年第5期307-309,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
关键词 端粒酶 端粒酶逆转录酶 核酶 抗体
分类号 R730.5 [医药卫生—肿瘤]
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参考文献17

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二级参考文献23

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深圳中西医结合杂志
2004年 第5期

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