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骨髓干细胞移植在心血管疾病中的应用 被引量：6

Application of Mesodermal Stem Cell Transplantation in Cardiovascular Diseases
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摘要 近年来的研究表明 ,骨髓干细胞向心肌细胞分化已成为可能 ,动物模型及临床应用均证实 。 Newly many studies show that mesodermal stem cell can be differentiated into cardiomyocyte,which will be much benefit in cardiovascular diseases.Both animal trial and clinic application have certificated mesodermal stem cell transplantation can improve ischemic cardiomyocyte and heart function.
作者 胡咏梅 罗羽慧 李法琦
机构地区 重庆医科大学附属第一医院
出处 《心血管病学进展》 CAS 2003年第1期38-44,共7页 Advances in Cardiovascular Diseases
关键词 骨髓干细胞移植 心血管疾病 临床应用 心肌梗死 骨髓干细胞 心功能不全 mesodermal stem cell,cell transplantation
分类号 R54 [医药卫生—心血管疾病] R457 [医药卫生—治疗学]
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参考文献16

  • 1[1]Makino S, Fukuda K, M iyoshi S, et al. Cardiomyocytes can be generated from marrow stromal cells in vitro [J]. J Clin Invest, 1999,103:697-705.
  • 2[2]Fukuda K. Development of regenerative oardiomyocytes from mesenchymal stem cells for cardiovascular tissue engineering[J]. Artif Organs ,2001,25: 187-193.
  • 3[3]Zibaitis A, Greentree D, Ma F, et al. Myocardial regeneration with satellite cell implantation [J]. Transplant Proc, 1994,26:3294.
  • 4[4]Watanabe E, Smith DMJ, Delcarpio JB, et al. Cardiomyocyte transplantation in a porcine myocardial infarction model[J]. Cell Transplant, 1998,7:239-246.
  • 5[5]Sohwarz ER,Patterson M,Kloner RA,et al. Cardiomyocyte transplantation-a cell replacement for repair of myocardial infarction? Z Kaidiol[J]. Review German,1998,87:1-7.
  • 6[6]Jla ZQ,Mickle DA,Weisel RD,et al. Transplanted cardiomyocytes survive in scar tissue and improve heart function[J]. Transplant Prot,1997.29:2093-2094.
  • 7[7]Matsushita T,Oyarnada M,Kurota H,et al. Formation of cell junctions between grafted and lost cardiomyoeytes st the border zone of rat myocardial infarction[J]. Circulation, 1999,100 ( 19 suppl ): Ⅱ262- Ⅱ 268.
  • 8[9]Asahara T, Murohara T, Sullivan A, et al. Isolation of putative progenitor endothelial cells for angiogenesis [ J ]. Science, 1997,275 :964-967.
  • 9[10]Kamihata H. Matsubara R, Nishiue T, et al. Implantation of bone marrow mononuclear cells into ischemic myocardium enhances collateral perfusion and regional function via side supply of angioblasts, angiogenic ligands ,and cytokines[ J ].Circulation,2001,104:1046-1052.
  • 10[11]Tomita S,Li RK,Weieel RD,et al. Antologous transplantation of bone marrow cells improve damaged heart function [J ]. Circulation, 1999,100 (19 suppl ):Ⅱ 247- Ⅱ 256.

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心血管病学进展
2003年 第1期

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