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国产盐酸莫索尼定治疗原发性高血压疗效的临床观察 被引量：1

Clinical effect of moxonidine made in China in the treatment of patients with essential hypertension
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摘要 目的：评价国产盐酸莫索尼定(商品名：奥必特)治疗原发性高血压的临床疗效。方法：对50例新发现的1、2级原发性高血压患者用国产盐酸莫索尼定治疗4～6周后比较用药前后的临床疗效及耐受性。结果：盐酸莫索尼定治疗四周后血压平均下降33/15±9/4mmHg (P<0.01)，总有效率为92%。用药四周后血压下降达标（<140／90mmHg以下者）31例，达标率为62%。未见严重不良反应。结论：国产盐酸莫索尼定治疗原发性高血压疗效确切，不良反应少、耐受性好，值得临床试用。 Objective: To evaluate the clinical effect of moxonidine(made in Chengdu,China) in the treatment of patients with essential hypertension. Methods: 50 patients with essential hypertension were treated with moxonidine for 4 to 6 weeks. Results: After treatment with moxonidine, BP of the patients were reduced significantly by 33/15±9/4mmHg (P<0.01). The total effective rate was 92%. Conclusion: Moxonidine made in China is effective in the treatment of essential hypertension.
作者 陈明 张义全 罗素新 邓国岚 陈运贞
机构地区 重庆医科大学临床学院心血管内科 四川省永荣矿务局职工总医院内科
出处 《重庆医科大学学报》 CAS CSCD 2002年第4期471-472,共2页 Journal of Chongqing Medical University
关键词 盐酸莫索尼定 治疗 原发性高血压 疗效 临床观察 Moxonidine Hypertension Treatment
分类号 R544.1 [医药卫生—心血管疾病] R972. [医药卫生—药品]
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参考文献5

  • 1[1]BNC. Prichard. pharmacology and clinical use of mononidine, a new centrally acting simpatholytic antiherpertensive agent[J]. J Human Hyper, 1997;11(s1):29-45.
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同被引文献9

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  • 6陈源源,孙宁玲,郭丹杰,吴彦,杨松娜,周慧青.两种国产莫索尼定降压疗效的比较[J].中国临床药理学杂志,2001,17(2):91-93. 被引量：1
  • 7梁英姿,王林,黄体钢,李飞雪,周丽娟.盐酸莫索尼定治疗原发性高血压Ⅱ期临床试验总结[J].实用心脑肺血管病杂志,2003,11(3):163-165. 被引量：2
  • 8姚雪艳,陈君柱,朱建华,胡晓晟,刘忠.评价莫索尼定在原发性高血压患者中的降压疗效[J].浙江医学,2003,25(7):407-409. 被引量：2
  • 9杨春娥,陈苏宁,李桂珍.莫索尼定片治疗高血压病的疗效观察[J].心脏杂志,2003,15(6):532-533. 被引量：1

引证文献1

重庆医科大学学报
2002年 第4期

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