摘要
便秘型肠易激综合征(irritable bowel syndrome with constipation,IBS-C)主要表现为腹痛、排便不畅或大便次数减少,西药主要以解痉药、氯离子通道激活剂、鸟苷酸环化酶激活剂等药物为主,但症状易反复,中医治疗逐渐成为IBS-C的潜在疗法。基于肝脾同调治法,从理法方药结合现代实验数据研究的角度,认为“白术-白芍”药对在IBS-C的治疗中应用值得推广,以期为IBS-C的治疗提供标本兼治、简便有效的中医思路。
Irritable bowel syndrome with constipation(IBS-C)is clinically characterized by abdominal pain,difficulty in defecation,or reduced bowel frequency.At present,Western pharmacological treatments primarily include antispasmodics,chloride channel activators,and guanylate cyclase-C agonists.However,these therapies often fail to prevent symptom recurrence.In contrast,Traditional Chinese Medicine has gained recognition as a potential therapeutic approach for IBS-C.Based on the liver-spleen harmonizing therapeutic principle and the integration of TCM principles(syndrome differentiation,therapeutic strategies,formula composition,and herb selection)with modern experimental evidence,the herb pair Atractylodes macrocephala-Paeonia lactiflora demonstrates significant clinical value in IBS-C management.This combination is proposed as a promising TCM intervention to achieve holistic efficacy,simultaneously addressing symptoms and root causes,while offering a safe,convenient,and effective therapeutic paradigm for IBS-C.
作者
蔡洁
李定祥
CAI Jie;LI Dingxiang(The First Clinical College of TCM,Hunan University of Traditional Chinese Medicine,Changsha 410208,China;Hunan University of Traditional Chinese Medicine,Changsha 410208,China)
出处
《陕西中医药大学学报》
2026年第2期55-59,共5页
Journal of Shaanxi University of Chinese Medicine
基金
湖南省科技创新团队项目(2020RC4050)。
关键词
白术
白芍
便秘型肠易激综合征
肝脾同调
atractylodes macrocephala
paeonia lactiflora
irritable bowel syndrome with constipation
coordinated regulation of the liver and spleen
