摘要
目的:对比腕踝针联合阿片类药物与单纯阿片类药物治疗癌痛的效果。方法:选取2023年1月—2025年6月大连医科大学附属第二医院、大连市中医医院肿瘤科收治的中晚期癌症患者500例,通过随机数字表法分为对照组和试验组,各250例。对照组应用阿片类药物镇痛,试验组在对照组基础上加用腕踝针治疗。比较两组疼痛强度、爆发痛发生频次及不良反应发生率,统计试验组腕踝针穿刺部位红肿、渗血、皮下血肿、晕针等现象发生情况。结果:治疗后,试验组静息痛疼痛数字评分法评分、活动痛疼痛数字评分法评分均低于对照组(P<0.001)。治疗后,试验组爆发痛发生频次低于对照组(P<0.001)。试验组不良反应总发生率低于对照组(P<0.001)。试验组患者未发生腕踝针穿刺部位红肿、渗血、皮下血肿、晕针等现象。结论:腕踝针联合阿片类药物治疗中晚期癌症患者癌痛的效果显著,可减少爆发痛频次,降低不良反应发生率,安全性较好。
Objective:To compare the effect of wrist-ankle acupuncture combined with opioid drugs and pure opioid therapy in the treatment of cancer pain.Methods:A total of five hundred patients with advanced cancer who were admitted to the department of oncology of the Second Affiliated Hospital of Dalian Medical University and Dalian Hospital of Traditional Chinese Medicine from January 2023 to June 2025 were selected.They were divided into the control group and the experimental group by random number table method,with two hundred and fifty cases in each group.The control group received analgesia with opioid drugs,while the experimental group received additional treatment with wrist-ankle acupuncture in addition to the measures taken by the control group.The pain intensity,the frequency of explosive pain occurrence,and the incidence of adverse reactions between the two groups were compared.The occurrence of phenomena such as redness and swelling at the puncture site,bleeding,subcutaneous hematoma,and fainting was statistically analyzed in the experimental group.Results:After the intervention,the score of the namerical rating scale score for resting pain,and the score of the namerical rating scale score for activity-induced pain in the experimental group were all lower than those in the control group(P<0.001).After the treatment,the frequency of breakthrough pain in the experimental group was lower than that in the control group(P<0.001).The total incidence of adverse reactions in the experimental group was also lower than that in the control group(P<0.001).The patients in the experimental group did not experience any symptoms such as redness,swelling,bleeding,subcutaneous hematoma,or fainting at the site of the wrist-ankle acupuncture.Conclusion:The combination of wrist-ankle acupuncture and opioid drugs in the treatment of cancer pain in patients with advanced cancer has a significant effect.It can reduce the frequency of breakthrough pain and lower the incidence of adverse reactions,with good safety.
作者
由彩霞
王露
王静丹
张建华
沈桐
You Caixia;Wang Lu;Wang Jingdan;Zhang Jianhua;Shen Tong(Department of Nursing,the Second Affiliated Hospital of Dalian Medical University,Dalian 116000,Liaoning Province,China;Department of Nursing,Dalian Hospital of Traditional Chinese Medicine,Dalian 116000,Liaoning Province,China)
出处
《中外医药研究》
2026年第1期118-120,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
基金
大连市医学科学研究计划项目(编号:20Z12011)。
关键词
腕踝针
阿片类药物
癌痛
疼痛
不良反应
Wrist-ankle acupuncture
Opioid drugs
Cancer pain
Pain
Adverse reactions
