摘要
目的探讨机械取栓后超早期醒脑开窍针刺治疗急性大血管闭塞性脑梗死的临床疗效。方法选取2018年3月—2023年12月无锡市中医医院神经外科收治的117例急性大血管闭塞性脑梗死患者为研究对象,根据治疗方案将其分为研究组58例和对照组59例。对照组患者机械取栓后72 h予以醒脑开窍针刺治疗,研究组患者机械取栓后12~24 h予以醒脑开窍针刺治疗,两组均治疗4周。比较两组治疗前后美国国立卫生研究院卒中量表(NIHSS)评分、改良Rankin量表(mRS)评分、改良Barthel指数、实验室检查指标(D-二聚体、同型半胱氨酸)。结果治疗后,两组NIHSS、mRS评分分别低于本组治疗前,改良Barthel指数分别高于本组治疗前,且研究组NIHSS、mRS评分低于对照组,改良Barthel指数高于对照组(P<0.05)。治疗后,两组D-二聚体、同型半胱氨酸分别低于本组治疗前,且研究组低于对照组(P<0.05)。结论机械取栓后超早期(12~24 h)醒脑开窍针刺可减轻急性大血管闭塞性脑梗死患者的神经功能缺损程度,提高日常生活活动能力,降低血栓负荷,改善血管内皮功能。
Objective To explore the clinical efficacy of ultra early consciousness-restoring and orifice-opening acupuncture after mechanical thrombectomy in the treatment of acute large vessel occlusion cerebral infarction.Methods A total of 117 patients with acute large vessel occlusion cerebral infarction admitted to Department of Neurosurgery of Wuxi Traditional Chinese Medicine Hospital from March 2018 to December 2023 were selected as the research subjects,and the patients were divided into the study group(n=58)and the control group(n=59)according to treatment plans.The patients in the control group received consciousness-restoring and orifice-opening acupuncture at 72 hours after mechanical thrombectomy,while the patients in the study group received consciousness-restoring and orifice-opening acupuncture at 12-24 hours after mechanical thrombectomy.Two groups were treated for 4 weeks.The National Institutes of Health Stroke Scale(NIHSS)score,modified Rankin Scale(mRS)score,modified Barthel Index,and laboratory indicators(D-dimer,homocysteine)before and after treatment were compared between the two groups.Results After treatment,the NIHSS and mRS scores of the two groups were lower than those before treatment,and the modified Barthel Index was higher than that before treatment,the NIHSS and mRS scores in the study group were lower than those in the control group,and the modified Barthel Index was higher than that in the control group(P<0.05).After treatment,the D-dimer and homocysteine of the two groups were lower than those before treatment,and the D-dimer and homocysteine in the study group were lower than those in the control group(P<0.05).Conclusion Ultra early consciousness-restoring and orifice-opening acupuncture(12-24 h)after mechanical thrombectomy can improve the degree of neurological dysfunction and daily living activities of patients with acute large vessel occlusion cerebral infarction,reduce thrombus load,and improve vascular endothelial function.
作者
姜立先
吴春富
梁建广
金东
何新俊
赵义纯
JIANG Lixian;WU Chunfu;LIANG Jianguang;JIN Dong;HE Xinjun;ZHAO Yichun(Department of Neurosurgery,Wuxi Traditional Chinese Medicine Hospital,Wuxi 214000,China;Department of Neurology,Wuxi Hospital of Traditional Chinese Medicine,Wuxi 214000,China)
出处
《实用心脑肺血管病杂志》
2026年第4期37-40,45,共5页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
基金
江苏省中医药学会科研项目(ZXFZ2024035)。
关键词
脑梗死
醒脑开窍
大血管闭塞
机械取栓
Brain infarction
Consciousness restoring for resuscitation
Intracranial large vessel occlusion
Mechanical thrombectomy
