摘要
本试验以7日龄断奶的仔猪为对象,探讨以小麦水解蛋白(hydrolyzed wheat gluten,HWG)替代人工乳中不同比例的乳清浓缩蛋白(whey protein concentrate,WPC)对仔猪生长性能、养分代谢、免疫功能和抗氧化能力的影响。试验选取45头健康的7日龄“杜×长×大”阉公猪,按照体重相近的原则随机分为4个处理,即对照组(n=15)、33%HWG组(n=10)、66%HWG组(n=10)和100%HWG组(n=10),分别饲喂4种人工乳,即将不同比例的HWG分别替代对照组人工乳中的WPC,比例分别为0%、33%、66%和100%,试验期为13 d。结果表明,HWG替代人工乳中WPC会影响仔猪的生长性能、氮代谢、脂肪代谢、肾功能、免疫功能和抗氧化能力;与对照组相比,HWG替代WPC比例为66%和100%显著降低仔猪平均日采食量和平均日增重(P<0.05),显著提高了仔猪料重比和腹泻指数(P<0.05),显著减少血清肌酐(P<0.05),显著提升了血清丙二醛水平(P<0.05);此外,HWG替代WPC比例为66%时血清免疫球蛋白A和M水平也显著降低(P<0.05);替代比例为100%时,血清高密度脂蛋白胆固醇水平显著升高(P<0.05)。当HWG替代WPC比例为33%仅表现为显著提高仔猪血清尿素和高密度脂蛋白胆固醇水平(P<0.05)。综上所述,在人工乳中使用HWG替代不同比例WPC,可能不利于超早期断奶仔猪的生长性能、养分代谢、免疫功能和抗氧化功能,但当添加比例为33%时负面影响不显著。
In this experiment,the piglets weaned at 7 days of age were used,and the aim was to determine the effect which hydrolyzed wheat gluten(HWG)replacing different doses of whey protein concentrate(WPC)in artificial milks on growth performance,nutrient metabolism,immune function and antioxidant capacity of piglets.Forty-five healthy crossbred(Duroc×Landrace×Yorkshire)piglets at 7 days of age were randomly allotted into four treatments,including control group(n=15),33%HWG group(n=10),66%HWG group(n=10),and 100%HWG group(n=10),which were fed the artificial milks that HWG replaced 0%,33%,66%and 100%WPC for 13 days,respectively.The results showed that HWG replacing WPC in artificial milks could affect growth performance,nitrogen metabolism,lipid metabolism,kidney function,immune function and antioxidant capacity in piglets.Compared with the piglets of control group,HWG replacing 66%and 100%WPC significantly reduced average daily feed intake and average daily gain(P<0.05),significantly enhanced feed to gain ratio and diarrhea index(P<0.05),significantly decreased serum creatinine(P<0.05),and significantly increased serum malondialdehyde concentrations(P<0.05)in piglets.In addition,serum immunoglobulin A and M levels were significantly reduced(P<0.05)when 66%of WPC was replaced by HWG,and serum high density lipoprotein cholesterol levels were significantly increased(P<0.05)when 100%of WPC was replaced by HWG.Compared with the piglets of control group,serum urea and high density lipoprotein cholesterol levels were significantly higher in the piglets fed the artificial milk that HWG replaced 33%WPC(P<0.05).In summary,HWG replacing different doses of WPC in artificial milks might be not conducive to growth performance,nutrient metabolism,immune function and antioxidant capacity in the early-weaned piglets,but when HWG replacing 33%WPC in artificial milks had not significantly negative effect on piglets.
作者
张斐然
邓为
向丰禺
黄冰
李智行
范祥奇
谭大雁
毛湘冰
ZHANG Feiran;DENG Wei;XIANG Fengyu;HUANG Bing;LI Zhihang;FAN Xiangqi;TAN Dayan;MAO Xiangbing(Key Laboratory of Animal Disease-Resistant Nutrition of Sichuan Province,Key Laboratory of Animal Disease-Resistant Nutrition and Feed of Ministry of Agriculture and Rural Affairs,Key Laboratory of Animal Disease-Resistance Nutrition of Ministry of Education,Animal Nutrition Institute,Sichuan Agricultural University,Chengdu 611130,China;College of Animal Science and Technology,Sichuan Agricultural University,Chengdu 611130,China)
出处
《畜牧兽医学报》
北大核心
2026年第2期839-847,共9页
ACTA VETERINARIA ET ZOOTECHNICA SINICA
基金
四川省科技计划项目(2021ZDZX0011)。
关键词
小麦水解蛋白
仔猪
生长性能
代谢
免疫功能
抗氧化能力
hydrolyzed wheat gluten
piglets
growth performance
metabolism
immune function
antioxidant capacity
