摘要
中药发酵作为传统炮制方法之一,借助微生物的代谢作用可改变药物成分及其药性,从而影响其药效和临床应用价值。我国在发酵中药的研究和应用方面历史悠久,更是最早采用该技术的国家之一。随着现代微生物工艺和发酵工程的发展,豆豉类饮片在治疗肠道疾病、溶血栓等方面的疗效被人们熟知。其中淡豆豉作为豆豉类饮片的代表性发酵饮片,更是以中药饮片的形式被收载于2025年版《中国药典》。本文系统梳理了豆豉类饮片的研究进展,从药效成分、药理作用、临床应用、炮制工艺及质量标准等方面对豆豉类饮片进行归纳和分析,为豆豉类及其发酵饮片相关研究提供参考。
As one of the traditional processing methods,fermentation in traditional Chinese medicine can alter the composition and properties of drugs through the metabolic action of microorganisms,thereby influencing their efficacy and clinical application value.China has a long history in the research and application of fermented traditional Chinese medicine,and is one of the earliest countries to adopt this technology.With advancements in modern microbial technology and fermentation engineering,the therapeutic effects of douchi herbal pieces—such as treating intestinal diseases and thrombolysis—have become widely recognized.Among them,dan douchi(light-fermented soybean),as a representative fermented soybean(douchi)herbal piece,has been officially included in the 2025 edition of the Chinese Pharmacopoeia as a standardized traditional Chinese medicine herbal pieces.This article systematically reviews the research progress of douchi herbal pieces,summarizing and analyzing their active components,pharmacological effects,clinical applications,processing techniques,and quality standards,providing references for related research on douchi herbal pieces and other fermented herbal pieces.
作者
袁伟
张定堃
陈培武
翁美芝
尹炜
于喆
钱丽梅
宋细忠
YUAN Wei;ZHANG Dingkun;CHEN Peiwu;WENG Meizhi;YIN Wei;YU Zhe;QIAN Limei;SONG Xizhong(Jiangxi University of Traditional Chinese Medicine,Nanchang Jiangxi 330004,China;State Key Laboratory of Southwestern Chinese Medicine Resources,Chengdu University of Traditional Chinese Medicine,Chengdu Sichuan 611137,China;Nanchang Jisheng Pharmaceutical Co.,Ltd,Nanchang Jiangxi 330115,China;Jiangxi Fangzhu Pharmaceutical Co.,Ltd,Xinyu Jiangxi 338000,China)
出处
《药品评价》
2025年第11期1419-1426,共8页
Drug Evaluation
关键词
豆豉类饮片
活性成分
药理作用
临床应用
质量标准
Fermented soybean(douchi)herbal pieces
Active ingredients
Pharmacological effects
Clinical applications
Quality standards
