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非侵入性神经调控治疗偏头痛的研究进展

Research progress in non-invasive neuromodulation for migraine treatment
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摘要 偏头痛是一种常见的特发性慢性神经血管疾病,被世卫组织列为全球致残性疾病第7位,为患者及家庭带来沉重负担。虽然目前临床仍普遍应用药物进行预防和治疗,但部分患者存在药物禁忌证、药物不良反应、疗效欠佳等情况,因此偏头痛的神经调控治疗再次引起研究者的关注。非侵入性神经调控治疗具有非侵入性、操作简单、不良反应小、自我管理等优势,如经皮神经电刺激、经颅磁刺激、经颅直流电刺激、远程电神经调控等,为偏头痛患者,尤其是难治性偏头痛患者的预防和治疗带来了更多的可能性。该文综述非侵入性神经调控在偏头痛治疗中的研究进展,旨在为临床工作及进一步研究提供参考。 Migraine is a common idiopathic chronic neurovascular disease,ranked as the seventh leading cause of disability worldwide by the World Health Organization,imposing a heavy burden on patients and their families.Although pharmacological interventions remain the primary clinical approach for prevention and treatment,some patients face contraindications,adverse drug reactions,or suboptimal efficacy.Consequently,neuromodulation therapies for migraine have garnered renewed research attention.Non-invasive neuromodulation therapy,such as transcutaneous electrical nerve stimulation,transcranial magnetic stimulation,transcranial direct current stimulation,and remote electrical neuromodulation,has the advantages of non-invasive,simple operation,few adverse reactions,and self-management.It brings more directions for the prevention and treatment of migraine patients,especially those with refractory migraine.This article reviews the research progress of non-invasive neuromodulation in the treatment of migraine,aiming to provide reference for clinical work and further research.
作者 张晓俊 陈子蒙 郎丽英 王炎强 ZHANG Xiaojun;CHEN Zimeng;LANG Liying;WANG Yanqiang(The Second Department of Neurology,Affiliated Hospital of Shandong Second Medical University,Weifang,Shandong 261000,China;School of Clinical Medicine,Shandong Second Medical University,Weifang,Shandong 261000,China)
出处 《现代医药卫生》 2026年第2期412-416,共5页 Journal of Modern Medicine & Health
关键词 经皮神经电刺激 经颅磁刺激 偏头痛 难治性偏头痛 综述 Transcutaneous electrical nerve stimulation Transcranial magnetic stimulation Migraine Refractory migraine Review
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