摘要
目的探讨温经通脉法结合复合型药物股动脉注射治疗下肢动脉硬化闭塞症(ASO)的有效性与安全性。方法选取2024年6月~2025年5月在我院血管外科就诊的ASO患者120例,按随机数字表法分为观察组和对照组,每组60例。对照组采用常规药物治疗,观察组采用温经通脉法结合复合型药物股动脉注射治疗。比较两组患者治疗后的临床疗效、下肢动脉血管内径、踝肱指数(ABI)以及不良反应发生情况。结果观察组的总有效率为91.67%,高于对照组的75.00%,组间总有效率比较差异显著(P<0.05);治疗前,两组患者下肢动脉内径无显著差异(P>0.05);观察组治疗后的下肢动脉内径(3.67±0.45)mm,高于对照组(2.85±0.38)mm(P<0.05);治疗前,两组患者ABI值比较无显著差异(P>0.05);观察组治疗后的ABI(0.88±0.12),高于对照组(0.69±0.10)(P<0.05);观察组的不良反应率为8.33%,低于对照组的20.00%,组间不良反应发生率比较差异显著(P<0.05)。结论临床为下肢动脉硬化闭塞症患者实施温经通脉法结合复合型药物股动脉注射治疗,安全可靠,能显著改善患者下肢血管状况。
Objective To investigate the efficacy and safety of the combination of warm meridian and vascular therapy with composite drug injection into the femoral artery for the treatment of lower limb arteriosclerosis obliterans(ASO).Methods 120 ASO patients who visited vascular surgery department from June 2024 to May 2025 were selected and randomly divided into an observation group and a control group using a random number table method,with 60 patients in each group.The control group was treated with conventional drugs,while the observation group was treated with a combination of warm meridian and vascular therapy combined with composite drug injection into the femoral artery.Compare the clinical efficacy,lower limb arterial diameter,ankle brachial index(ABI),and incidence of adverse reactions between two groups of patients after treatment.Results The total effective rate of the observation group was 91.67%,which was higher than the control group's 75.00%.The difference in total effective rate between groups was significant(P<0.05).Before treatment,there was no significant difference in the inner diameter of lower limb arteries between the two groups(P>0.05).The inner diameter of the lower limb arteries in the observation group after treatment was(3.67±0.45)mm,which was higher than that in the control group(2.85±0.38)mm(P<0.05).Before treatment,the ABI values of the two groups were no significant difference(P>0.05).The ABI of the observation group after treatment(0.88±0.12)was higher than that of the control group(0.69±0.10)(P<0.05).The adverse reaction rate of the observation group was 8.33%,which was lower than the control group's 20.00%.The difference in incidence of adverse reactions rate between the groups was significant(P<0.05).Conclusion The clinical treatment of lower limb arteriosclerosis obliterans patients with warm meridian and vascular therapy combined with composite drug femoral artery injection is safe and reliable,and can significantly improve the vascular condition of the lower limbs.
作者
张敏道
陈浩
单延龙
王峰
吴立伟
ZHANG Mindao;CHEN Hao;DAN Yanlong;WANG Feng;WU Liwei(Clinical Integration of Traditional Chinese and Western Medicine at Heilongjiang University of Traditional Chinese Medicine,Harbin 150000,China)
出处
《四川中医》
2026年第2期68-72,共5页
Journal of Sichuan of Traditional Chinese Medicine
基金
黑龙江省中医药科研项目(ZHY2024-142)。
关键词
下肢动脉硬化闭塞症
温经通脉法
有效性
安全性
Lower limb arteriosclerosis obliterans
Warm meridian and vascular therapy
Effectiveness
Security
