摘要
目的探究支架辅助弹簧圈栓塞术与单纯弹簧圈栓塞术在颅内破裂动脉瘤(RIA)中的应用价值。方法选取2021年12月至2023年11月南阳市中心医院收治的71例RIA患者资料开展回顾性分析,根据手术方法分为研究组(37例)和常规组(34例)。比较两组围手术期相关指标、栓塞效果、手术前后氧化应激指标[超氧化物歧化酶(SOD)、丙二醛(MDA)、晚期氧化蛋白产物(AOPP)]、美国国立卫生研究院卒中量表(NIHSS)评分、改良Rankin量表(mRS)评分及并发症情况。结果研究组手术时间、住院时间短于常规组,术中出血量低于常规组,住院费用高于常规组,术后即刻栓塞效果优于常规组(P<0.05);术后3、7 d,研究组血清SOD高于常规组,MDA、AOPP低于常规组(P<0.05);术后3、6个月,研究组NIHSS评分、mRS评分低于常规组(P<0.05);两组并发症发生率比较,差异无统计学意义(P>0.05)。结论支架辅助弹簧圈栓塞术治疗RIA效果优于单纯弹簧圈栓塞术,可改善患者预后,但会增加患者经济负担。
Objective To explore the application value of stent assisted coil embolization and coil embolization alone in the treatment of ruptured intracranial aneurysms(RIA).Methods The data of 71 patients with RIA in Nanyang Central Hospital from December 2021 to November 2023 were retrospectively analyzed,and they were divided into study group(37 cases)and conventional group(34 cases)according to surgical methods.The perioperative related indexes and embolization effect were compared between the two groups,as well as the levels of oxidative stress indexes[superoxide dismutase(SOD),malondialdehyde(MDA),advanced oxidation protein product(AOPP)],National Institute of Health stroke scale(NIHSS)score,modified Rankin scale(mRS)score before and after operation,and complications were compared between the two groups.Results The operation time and hospitalization time of the study group were shorter than those of the conventional group,the intraoperative blood loss was lower than that of the conventional group,the hospitalization cost was higher than that of the conventional group,and the immediate postoperative embolization effect was better than that of the conventional group(P<0.05).At 3 and 7 days after operation,serum SOD in the study group was higher than that in the conventional group,while MDA and AOPP in the study group were lower than those in the conventional group(P<0.05).At 3 and 6 months after operation,the NIHSS score and mRS score of the study group were lower than those of the conventional group(P<0.05).There was no statistical difference in the incidence of complications between the two groups(P>0.05).Conclusion The effect of stent assisted coil embolization in the treatment of RIA is better than that of coil embolization alone,which can improve the prognosis of patients,but will increase the economic burden of patients.
作者
邹巧鸽
康梅娟
杨银雪
周静
司肖曼
温昌明
刘义锋
ZOU Qiaoge;KANG Meijuan;YANG Yinxue;ZHOU Jing;SI Xiaoman;WEN Changming;LIU Yifeng(Neurology Interventional Ward,Nanyang Central Hospital,Nanyang 473001,China)
出处
《河南医学研究》
2026年第3期492-495,共4页
Henan Medical Research
关键词
颅内破裂动脉瘤
弹簧圈栓塞术
支架
氧化应激反应
预后
并发症
ruptured intracranial aneurysms
coil embolization
support
oxidative stress reaction
prognosis
complications
