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基于“三脏同治”探析“升降理论”在肾性蛋白尿治疗中的应用

A Discussion on the Application of the"Ascending-Descending Theory"in the Treatment of Renal Proteinuria Based on the Principle of"Simultaneous Treatment of Three Zang-organs"
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摘要 肾性蛋白尿属中医学“精微下泄”范畴,其核心病机在于肺、脾、肾三脏功能失常,导致气机升降失衡。肺失宣降则水精不布,脾失健运则清阳不升,肾失封藏则精微下泄,三者互为因果形成恶性循环。“升降出入”理论出自《素问·六微旨大论》,本文根据该理论提出三脏同治原则:肺主气机之枢,当以宣肃为要;脾为气机之轴,宜健运中州;肾司开阖之机,需固摄下焦。通过调节三脏气机升降,标本兼治,可有效减少尿蛋白漏出,改善肾功能,这可为治疗肾性蛋白尿提供新思路。 Renal proteinuria belongs to the category of"essence turbidity leakage"in traditional Chinese medicine.Its core pathogenesis lies in the dysfunction of the Three Zang-organs(lungs,spleen and kidneys),which leads to the imbalance of Qi movement in ascending and descending.If the lung fails to disperse and de-·20·scend Qi,the distribution of fluid nutrients will be impaired;if the spleen fails to transport and transform,clear yang will fail to ascend;if the kidney fails to consolidate and contain,essential substances will leak downward.These three conditions interact as both cause and effect,forming a vicious cycle.The theory of"ascending,de-scending,entering and exiting"originates from Su Wen·Liu Wei Zhi Da Lun(Plain Questions·Great Trea-tise on the Six subtle Essentials).This theory puts forward the principle of simultaneous treatment of the Three Zang-organs:the lung,as the pivot of Qi movement,should prioritize dispersion and descent;the spleen,as the axis of Qi movement,ought to transport and transform the middle energizer;the kidney,which governs the mechanism of opening and closing,needs to consolidate the lower energizer.By regulating the ascending and de-scending of Qi movement in the Three Zang-organs and treating both the symptoms and the root cause,effective reduction in protein leakage in urine,improvement in renal function,and a new therapeutic approach for renal proteinuria can be achieved.
作者 黄玉梅 秦应娟 蒋艳 HUANG Yumei;QIN Yingjuan;JIANG Yan(Guizhou University of Traditional Chinese Medicine,Guiyang 550025,Guizhou,China;Department of Nephrology,Bijie Hospital of Traditional Chinese Medicine,Bijie 551700,Guizhou,China)
出处 《贵州中医药大学学报》 2026年第1期16-21,共6页 Journal of Guizhou University of Traditional Chinese Medicine
基金 贵州省中医药管理局中医药、民族医药科学技术研究课题项目(QZYY-2025-157)。
关键词 三脏同治 升降理论 肾性蛋白尿 中医学 simultaneous treatment of Three Zang-organs theory of ascending and descending renal proteinuria traditional Chinese medicine
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