摘要
目的探究老年心血管疾病(CVD)住院患者体质量指数(BMI)与内在能力(IC)的关系。方法连续纳入2023年4月至10月于深圳市南山区人民医院住院的409例老年CVD患者为研究对象,根据IC评分将患者分为高IC组(n=174例)和低IC组(n=235例)。采用一般情况调查问卷、IC测量量表、握力计、查尔森合并症指数(CCI)量表对纳入患者进行分析。采用多因素logistic回归分析探讨BMI与IC间的相关性,采用限制性立方样条模型分析BMI与IC间的剂量-反应关系。采用SPSS 25.0和R 4.4.1软件进行数据分析。根据数据类型,组间比较分别采用t检验、秩和检验及χ^(2)检验。结果单因素分析结果显示,性别、教育程度、吸烟、饮酒、居住地、BMI、握力、舒张压和年龄校正的CCI与IC具有相关性(P<0.05)。多因素logistic回归模型发现体质量不足与IC呈负相关(RR=10.110,95%CI 1.270~80.484;P=0.029),超重(RR=0.383,95%CI 0.234~0.628;P<0.001)和肥胖(RR=0.473,95%CI 0.226~0.989;P=0.047)与IC呈正相关。限制性立方样条模型表明BMI和IC之间存在非线性关联(非线性P=0.0016,总体关联P<0.001),当BMI>23.9 kg/m^(2)时,可降低IC下降的风险。结论老年CVD患者BMI与IC呈非线性剂量反应关系,超重和肥胖可降低IC下降的发生风险。
Objective To investigate the relationship between body mass index(BMI)and intrinsic capacity(IC)in elderly inpa-tients with cardiovascular diseases(CVD).Methods A total of 409 elderly CVD patients hospitalized in Nanshan District People's Hospital from April to October 2023 were consecutively included as study subjects,and according to their IC score,they were divided into a high IC group(n=174)and a low IC group(n=235).General condition questionnaire,intrinsic capacity measurement scale,handgrip strength meter,and Charlson comorbidity index(CCI)index scale were used to survey the included patients.Multivariate logistic regression analysis was applied to explore the relationship between BMI and IC,and restricted cubic spline model was employed to analyze the dose-response relationship between BMI and IC.SPSS statistics 25.0 and R 4.4.1 were used for statistical analysis.Data comparison between two groups was performed using t test,rank-sum test orχ^(2) test depending on data type.Results Univariate analysis showed that IC is correlated with gender,education level,smoking,alcohol consumption,place of residence,BMI,handgrip strength,diastolic blood pressure(DBP),and age-adjusted CCI(a-CCI)(P<0.05).Multivariate logistic regression model revealed that under-weight was negatively associated with IC(RR=10.110,95% CI 1.270-80.484;P=0.029),and overweight(RR=0.383,95% CI 0.234-0.628;P<0.001)and obesity(RR=0.473,95%CI 0.226-0.989;P=0.047)were positively correlated with IC.Restricted cubic spline model showed a nonlinear association between BMI and IC(nonlinear P=0.0016,overall association P<0.001),and the risk of IC decline was reduced when BMI was greater than 23.9 kg/m^(2).Conclusion In elderly CVD patients,their BMI shows a nonlinear dose-response relationship with IC,and overweight and obesity can reduce the risk of IC decline.
作者
谢葵花
刘璞娉
周洁
许俊炜
张青
Xie Kuihua;Liu Puping;Zhou Jie;Xu Junwei;Zhang Qing(Wuhan University School of Nursing,Wuhan 430000,China;Department of Cardiology,Nanshan District People's Hospital of Shenzhen,Shenzhen 518000,Guangdong Province,China)
出处
《中华老年多器官疾病杂志》
2026年第1期31-35,共5页
Chinese Journal of Multiple Organ Diseases in the Elderly
基金
深圳市科技计划(JCY20220530141815035)。
关键词
老年人
心血管疾病
体质量指数
内在能力
aged
cardiovascular diseases
body mass index
intrinsic capacity
