摘要
目的分析在册严重精神障碍患者死亡及减寿情况。方法2024年1月利用宁波市精神卫生信息管理系统收集2012—2022年宁波市海曙区在册严重精神障碍死亡患者数据,采用Joinpoint 5.0软件计算死亡率年度变化百分比(annual percent change,APC),采用logistic回归分析模型分析患者死亡的影响因素,采用潜在减寿年数(potential years of life lost,PYLL)等分析患者寿命损失。结果2012―2022年宁波市海曙区报告在册严重精神障碍死亡患者共808人,年均报告死亡率、标化死亡率分别为7.32/10万、7.34/10万,两者变化趋势均有统计学意义(APC=13.05%,APC=13.48%;均P<0.05)。截至2022年12月31日,宁波市海曙区在册严重精神障碍患者总病死率为13.95%。与文盲/半文盲患者相比,小学、初中/中专、高中、大专及以上患者死亡风险更低(OR=0.41,OR=0.31,OR=0.22,OR=0.12;均P<0.001)。与首次发病年龄≤18岁患者相比,>18~<40岁、≥40岁患者死亡风险更高(OR=1.66,OR=2.01;均P<0.001)。死亡患者首位死因为躯体疾病(639例,79.08%),全部死因造成的PYLL为9640.84人年,标化潜在减寿年数(standardized potential years of life lost,SPYLL)为9210.58人年,潜在减寿率(potential years of life lost rate,PYLLR)为9.24‰,标化潜在减寿率(standardized potential years of life lost rate,SPYLLR)为8.91‰,平均减寿年数(average years of life lost,AYLL)为11.93年。精神分裂症患者PYLL、SPYLL、PYLLR、SPYLLR均最高(6163.33人年、5878.41人年、5.91‰、5.64‰),癫痫所致精神障碍患者的AYLL最高(15.93年)。结论海曙区在册严重精神障碍患者死亡率呈上升趋势,主要死因是躯体疾病,精神分裂症和癫痫所致精神障碍对患者寿命影响较大。
Objective To analyse mortality and life lost due to registered severe mental disorders patients.Methods All registered severe mental disorders deaths in Haishu District of Ningbo City were extracted from Ningbo Municipal Mental Health Information Management System from 2012 to 2022 on January 2024.Joinpoint 5.0 software was used to calculate the annual percent change(APC)of mortality,and logistic regression model was used to analyze the influencing factors of deaths.We used potential years of life lost(PYLL)and related measures to analyze patients'loss of life expectancy.Results A total of 808 registered severe mental disorders deaths were reported living in Haishu District from 2012 to 2022.The average annual reported mortality rate and standardized mortality rate were 7.32/100000 and 7.34/100000 respectively,and the trends of both were statistically significant(APC=13.05%,APC=13.48%;all P<0.05).Until December 31,2022,the total fatality rate of patients was 13.95%.Compared with illiterate/semi-literate patients,patients with primary school,junior high school/technical secondary school,high school,and college and above education had a lower risk of death(OR=0.41,OR=0.31,OR=0.22,OR=0.12;all P<0.001).Compared with patients with the first onset age≤18 years old,patients with the first onset age of>18 to<40 years old and≥40 years old had a higher risk of death(OR=1.66,OR=2.01;all P<0.001).The leading cause of deaths was somatic diseases(639 cases,79.08%).Additionally,PYLL,standardized potential years of life lost(SPYLL),potential years of life lost rate(PYLLR),standardized potential years of life lost rate(SPYLLR)and average years of life lost(AYLL)due to all causes of deaths were 9640.84 person-years,9210.58 person-years,9.24‰,8.91‰,and 11.93 years.PYLL,SPYLL,PYLLR and SPYLLR of schizophrenia deaths were the highest(6163.33 person-years,5878.41 person-years,5.91‰ and 5.64‰),and AYLL of epilepsy deaths was the highest(15.93 years).Conclusions The mortality of registered severe mental disorders patients in Haishu District was on the rise.The predominant cause of deaths was somatic diseases,and schizophrenia and epilepsy showed a great negative effect on the lifespan.
作者
袁月荣
杨红英
洪航
方挺
王云
陈亚萍
王海滨
YUAN Yuerong;YANG Hongying;HONG Hang;FANG Ting;WANG Yun;CHEN Yaping;WANG Haibing(Department of Psychiatry and Mental Health,Haishu District Center for Disease Prevention and Control,Ningbo 315000,China;Department of Public Health,The Affiliated Kangning Hospital of Ningbo University,Ningbo 315200,China;School of Public Health,School of Medicine,Ningbo University,Ningbo 315211,China;Department of Administrative Office,Ningbo Psychiatric Hospital,Ningbo 315032,China)
出处
《中华疾病控制杂志》
北大核心
2025年第12期1405-1410,1472,共7页
Chinese Journal of Disease Control & Prevention
基金
2023年度宁波市甬江人才工程领军拔尖人才培养项目。
关键词
严重精神障碍
死亡率
死因
减寿分析
Severe mental disorders
Mortality
Cause of death
Analysis of life lost
