摘要
金黄色葡萄球菌是院内获得性感染的主要病原体之一,当它侵入血液系统时,就会导致金黄色葡萄球菌血流感染(SABI)。SABI常见的预后相关因素包括性别、是否有基础疾病,与SABI的预后关系密切;年龄也是影响预后的独立危险因素;感染耐甲氧西林金黄色葡萄球菌(MRSA)病人预后差,而且不同感染部位导致的血流感染预后情况也不同;SABI病人血清白细胞介素-10值越高病人预后越差;最后病人接受治疗情况等都对病人预后有影响。分析SABI预后相关因素并建立评估预后的预测模型,可以帮助临床医生制定最佳的治疗方案和监护措施。
Staphylococcus aureus,especially the methicillin-resistant strain(MRSA),is a leading cause of hospital-acquired infections.When it enters the bloodstream,it leads to Staphylococcus aureus bloodstream infection(SABI),a condition with significant clinical implications.Key prognostic factors for SABI include gender,underlying medical conditions,and age,with the latter being an independent risk factor that significantly affects outcomes.Patients suffering from MRSA-associated SABI typically have a poorer prognosis.Additionally,the site of infection can lead to different prognostic outcomes in SABI cases.Higher serum levels of interleukin-10 in patients are associated with worsening prognoses.The treatment protocols applied are crucial in influencing the overall prognostic outcomes.A thorough analysis of these prognostic factors and the development of predictive models are essential for enabling clinicians to devise optimal treatment strategies and monitoring protocols.
作者
秦泽辉
叶莉萍
田行瀚
QIN Zehui;YE Liping;TIAN Xinghan(Clinical Medicine School,Shandong Second Medical University,Weifang,Shandong 261000,China;Intensive Care Unit,Yulingding Hospital of Yantai,Yantai,Shandong 264000,China)
出处
《安徽医药》
2026年第2期236-241,共6页
Anhui Medical and Pharmaceutical Journal
基金
山东省医药卫生科技发展计划项目(2019WS281)。
关键词
金黄色葡萄球菌
血流感染
医院内感染
预后
预测模型
Staphylococcus aureus
Bloodstream infection
Hospital infection
Prognostic factors
Predictive model
