摘要
目的 分析不同弥散敏感系数(b值)下扩散加权成像-体素内不相干运动(DWI-IVIM)对前列腺癌(PCa)、前列腺增生(BPH)的鉴别价值。方法 采取回顾性研究,收集2022年8月至2024年3月医院收治的97例PCa及BPH患者的临床资料。所有患者均接受DWI-IVIM检查,根据不同b值组合分为低b值组(b=0、50、100、150、200、400、600 s/mm2)、高b值组(b=0、50、100、150、200、400、600、800、1 000、1 500、2 000 s/mm2),测得表观扩散系数(ADC)值、纯弥散系统(D值)、伪弥散系统(D*值)、灌注分数(f值),比较PCa与BPH组各参数值;绘制受试者工作特征(ROC)曲线,分析不同b值组合DWI-IVIM对PCa、BPH的鉴别价值。结果 PCa组低b值ADC值、低b值D值、高b值ADC值、高b值D值低于BPH组,PCa组低b值f值高于BPH组(P<0.05);2组低b值D*值、高b值D*值、高b值f值比较差异无统计学意义(P>0.05);绘制ROC曲线显示,低b值ADC值、低b值D值、低b值f值、高b值ADC值、高b值D值以及联合检测的曲线下面积(AUC)均>0.70,95%置信区间分别为(0.73,0.90)、(0.80,0.94)、(0.68,0.87)、(0.81,0.95)、(0.79,0.94)、(0.92,1.00)、(0.88,0.99),约登指数分别为0.53、0.60、0.47、0.66、0.62、0.85、0.78,灵敏度分别为1.00、0.91、0.59、0.98、0.89、0.91、0.96,特异度分别为0.53、0.69、0.88、0.69、0.72、0.94、0.82。结论低b值为主的DWI-IVIM成像与高b值为主的DWI-IVIM成像在PCa和BPH鉴别中均具有一定价值,且二者价值有所不同,可在临床诊断PCa及BPH时提供很好的指导。
Objective The value of diffusion-weighted imaging-incoherent motion(DWI-IVIM)in the differential diagnosis of prostate cancer(PCa)and benign prostatic hyperplasia(BPH)under different diffusion sensitivity coefficients(b values)was analyzed.Methods A retrospective study was conducted,the clinical data of 97 patients with PCa and BPH admitted to the hospital from August 2022 to March 2024 were collected.All patients underwent an DWI-IVIM examination.According to different b value combinations,they were divided into low b value group(b=0,50,100,150,200,400,600 s/mm2)and high b value group(b=0,50,100,150,200,400,600,800,1000,1500,2000 s/mm2).The ADC value,D value,D*value and f value were measured,and the parameters of PCa and BPH groups were compared.The receiver operating characteristic(ROC)curve was drawn to analyze the differential value of DWI-IVIM with different b values combinations for PCa and BPH.Results The low b-value ADC value,low b-value D value,high b-value ADC value and high b-value D value in the PCa group were lower than those in the BPH group,and the low b-value f value in the PCa group was higher than those in the BPH group(P<0.05).There were no significant difference in low b value D*value,high b value D*value and high b value f value between the two groups(P>0.05).ROC curve showed that the area under the curve(AUC)of low b value ADC value,low b value D value,low b value f value,high b value ADC value and high b value D value were 0.81,0.87,0.78,0.88 and 0.87,respectively.The 95%confidence interval was(0.73,0.90),(0.80,0.94),(0.68,0.87),(0.81,0.95),(0.79,0.94),(0.92,1.00)and(0.88,0.99),respectively.The Youden index was 0.53,0.60,0.47,0.66,0.62,0.85 and 0.78,respectively.The sensitivity was 1.00,0.91,0.59,0.98,0.89,0.91 and 0.96,respectively,and the specificity was 0.53,0.69,0.88,0.69,0.72,0.94 and 0.82,respectively.Conclusion DWI-IVIM imaging with low b value and DWI-IVIM imaging with high b value have a certain value in the differential diagnosis of PCa and BPH,and the value of the two is different,which can provide good guidance in the clinical diagnosis of PCa and BPH.
作者
付瑜莹
Fu Yuying(Zhenping County People's Hospital,Henan 474250,China)
出处
《实用医学影像杂志》
2025年第6期438-442,共5页
Journal of Practical Medical Imaging
关键词
前列腺肿瘤
前列腺增生
弥散敏感系数
扩散加权成像
体素内不相干运动
磁共振成像
Prostate neoplasms
Benign prostatic hyperplasia
Diffusion intensity
Diffusion-weighted imaging
Intravoxel incoherent motion
Magnetic resonance imaging
