摘要
全球每年因植物寄生线虫导致的农业经济损失超过3580亿美元,利用食线虫真菌防治线虫低毒环保,是实现绿色防控的有效手段。目前已知丝氨酸蛋白酶是食线虫真菌侵染线虫过程中的关键毒力因子。近年来,研究人员对与食线虫真菌致病相关的丝氨酸蛋白酶进行了广泛研究。本文总结了食线虫真菌丝氨酸蛋白酶研究现状,包括丝氨酸蛋白酶的分类、生化性质、结构特性以及催化、调控作用机制,并阐述了研究食线虫真菌丝氨酸蛋白酶的意义和存在的问题。
Agricultural economic losses caused by plant-parasitic nematodes exceed$358 billion annually worldwide.The use of nematophagous fungi to control nematodes is an environmentally friendly and low-toxicity strategy,offering an effective measures for sustainable pest management.It is well established that serine proteases play a crucial role as virulence factors during nematode infection.Recent studies have focused extensively on the serine proteases associated with the pathogenicity of nematophagous fungi.This paper reviews the current understanding of serine proteases in these fungi,including their classification,biochemical properties,structural characteristics,as well as their catalytic and regulatory mechanisms.Additionally,the significance of studying these serine proteases and the challenges that remain in this area are discussed.
作者
杨玉红
张秀君
吕卿
王禄山
何文兴
徐会连
YANG Yu-hong;ZHANG Xiu-jun;LV Qing;WANG Lu-shan;HE Wen-xing;XU Hui-lian(School of Biological Science and Technology,University of Jinan,Jinan 250022;State Key Laboratory of Microbial Technology,Shandong University,Qingdao 266237)
出处
《微生物学杂志》
北大核心
2025年第6期109-118,共10页
Journal of Microbiology
基金
山东省自然科学基金项目(ZR201911010063)
山东省重点研发计划项目(2021CXGC010803)
济南大学重大课题项目(1420707)。
关键词
食线虫真菌
丝氨酸蛋白酶
功能
晶体结构
生物防治
Nematophagous fungi
serine protease
sunction
srystal structure
siological control
