摘要
目的探究生理状态下腕部血管与组织力学特性对示波法血压测量的影响,为可穿戴血压计研发提供数据支持。方法采用磁共振成像获取加压状态下的腕部影像;利用超声弹性成像测量皮肤、肌肉和肌腱的弹性模量;并采集受试者测压包络曲线。通过分析腕部影像,评估腕部各组织力学特性对气囊压力的影响,并比较测压包络特征;同时,运用ABAQUS数值模拟方法分析腕部组织力学特性对示波法血压测量的影响。结果在腕带压力为100 mmHg(1 mmHg=0.133 kPa)时,腕部轮廓已趋于稳定,截面积较0 mmHg时减少约14%;不同志愿者之间腕部组织的平均弹性模量存在8.1 kPa的差异,该差异与肌肉的所占比例和弹性模量有较大相关性。数值模拟结果表明,组织平均弹性模量增大会导致示波法包络的最大值相应减小,与人体实测数据结果趋势一致。结论在加压时腕部组织的载荷与面积应变呈现显著的非线性关系,皮肤、脂肪和肌肉均对面积变化产生影响;组织平均弹性模量越大,示波法包络的最大值越小。
Objective To investigate the impact of the mechanical properties of wrist vasculature and tissues under physiological conditions on oscillometric blood pressure measurement and provide data supporting the development of wearable blood pressure monitors.Methods Magnetic resonance imaging(MRI)was used to obtain images of the wrist when the cuff was pressurized.Ultrasound elastography was employed to measure the elastic modulus of the skin,muscle,and tendon.The oscillometric envelopes of the subjects were collected.MRI images were analyzed to investigate the influence of mechanical properties of different tissues on oscillometric envelopes,and the characteristics of the oscillometric envelope were compared.Simulations were also conducted using ABAQUS to investigate the effect of wrist tissue mechanical properties on oscillometric blood pressure measurement.Results At a cuff pressure of 100 mmHg(1 mmHg=0.133 kPa),the wrist shape was stabilized,with the cross-sectional area reduced by approximately 14%compared with that at 0 mmHg.The average elastic modulus of wrist tissues among volunteers varied by 8.1 kPa and was strongly correlated with both muscle proportion and muscle stiffness.Simulation results showed that a higher average elastic modulus was associated with a lower peak amplitude of the oscillometric envelope.Conclusions During cuff compression,the load and area of strain of wrist tissues showed a clear nonlinear relationship,and the skin,fat,and muscle all contributed to the change in area.A higher average elastic modulus of the tissues corresponds to a smaller maximum amplitude of the oscillometric envelope.
作者
姚健
卢泰祺
刘雍陶
宋辉
韩丽莎
贺缨
YAO Jian;LU Taiqi;LIU Yongtao;SONG Hui;HAN Lisha;HE Ying(Key Laboratory of Ocean Energy Utilization and Energy Conservation of Ministry of Education,School of Energy and Power Engineering,Dalian University of Technology,Dalian 116024,Niaoling,China;Institute of Applied Mechanics,College of Aeronautics and Astronautics,Taiyuan University of Technology,Taiyuan 030024,China)
出处
《医用生物力学》
北大核心
2025年第6期1434-1442,共9页
Journal of Medical Biomechanics
基金
国家自然科学基金面上项目(51976026)。
关键词
磁共振成像
超声弹性成像
示波法包络
血压测量
腕部加压
magnetic resonance imaging
ultrasound elastography
oscillometric envelope
blood pressure measurement
cuff compression
