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改良B-Lynch缝合术对产后出血患者并发症发生率及凝血功能指标的影响

Effect of Modified B-Lynch Suture on the Incidence of Complications and Coagulation Function in Patients with Postpartum Hemorrhage
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摘要 目的 探究改良B-Lynch缝合术对产后出血患者并发症发生率及凝血功能指标的影响。方法 选择2021年8月-2023年8月在天津河东天铁医院接受治疗的106例产后出血产妇作为研究对象,通过随机数字表法将其分为研究组和对照组,每组53例。对照组采用卡前列素氨丁三醇联合子宫压迫缝合术进行治疗,研究组则采用卡前列素氨丁三醇联合改良B-Lynch缝合术进行治疗。对两组的临床指标(术中及术后24 h出血量、手术时间、住院时间、月经复潮时间)、凝血功能指标[活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)、纤维蛋白原(FIB)]、生育功能指标[抗苗勒管激素(AMH)、窦卵泡计数(AFC)、促卵泡激素(FSH)、雌二醇(E_(2))、黄体生成素(LH)]、子宫切除率,以及并发症发生率进行比较。结果 研究组在术中及术后24 h出血量、手术时间、住院时间、月经复潮时间均低于对照组(P<0.05)。研究组治疗后的FIB水平高于对照组,而PT、APTT水平均低于对照组(P<0.05)。研究组术后E2水平、AMH、AFC、FSH、LH水平均低于对照组(P<0.05)。研究组的并发症发生率低于对照组(P<0.05),而两组的子宫切除率比较,差异无统计学意义(P>0.05)。结论 采用改良B-Lynch缝合术治疗产后出血,临床效果确切,可有效减少产妇术中及术后的出血量,缩短手术时间、住院时间及月经复潮时间,改善患者凝血功能与生育功能,且具有较高的安全性。 Objective To explore the effect of modified B-Lynch suture on the incidence of complications and coagulation function in patients with postpartum hemorrhage.Methods A total of 106 parturients with postpartum hemorrhage who were treated in Tianjin Hedong Tiantie Hospital from August 2021 to August 2023 were selected as the research objects.They were divided into study group and control group by random number table method,with 53 parturients in each group.The control group was treated with carboprost tromethamine combined with uterine compression suture,while the study group was treated with carboprost tromethamine combined with modified B-Lynch suture.The clinical indexes(intraoperative and postoperative 24 h bleeding volume,operation time,hospitalization time,menstrual recovery time),coagulation function indexes[activated partial thromboplastin time(APTT),prothrombin time(PT),fibrinogen(FIB)],fertility function indexes[anti-mullerian hormone(AMH),antral follicle count(AFC),follicle stimulating hormone(FSH),estradiol(E2),luteinizing hormone(LH)],hysterectomy rate,and complication rate were compared between the two groups.Results The intraoperative and postoperative 24 h bleeding volume,operation time,hospitalization time and menstrual recovery time in the study group were lower than those in the control group(P<0.05).The FIB level of the study group after treatment was higher than that of the control group,while the PT and APTT were lower than those of the control group(P<0.05).The levels of E_(2),AMH,AFC,FSH and LH in the study group were lower than those in the control group(P<0.05).The incidence of complications in the study group was lower than that in the control group(P<0.05),but there was no significant difference in the hysterectomy rate between the two groups(P>0.05).Conclusion Modified B-Lynch suture is effective in the treatment of postpartum hemorrhage,which can effectively reduce the intraoperative and postoperative bleeding volume,shorten the operation time,hospitalization time and menstrual recovery time,improve the coagulation function and fertility function of patients,and has high safety.
作者 白建华 BAI Jianhua(Department of Obstetrics and Gynecology,Tianjin Hedong Tiantie Hospital,Tianjin 300000,China)
出处 《医学信息》 2025年第24期123-126,131,共5页 Journal of Medical Information
关键词 卡前列素氨丁三醇 改良B-LYNCH缝合术 产后出血 生育功能 凝血功能 Carboprost tromethamine Modified B-Lynch suture Postpartum hemorrhage Fertility function Coagulation function
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