摘要
目的:探讨急性脑梗死合并2型糖尿病患者糖化血红蛋白(HbA1c)水平与其早期神经功能损伤程度以及短期预后之间的相关性.方法:选取2021年7月至2023年10月本院收治的244例急性脑梗死合并2型糖尿病患者作为研究对象,根据HbA1c水平,将其分为研究组(n=46,HbA1c>8.2%)和对照组(n=178,HbA1c≤8.2%).比较两组患者临床资料、神经功能缺损情况[采用美国国立卫生研究院卒中量表(NIHSS)评估];对患者随访3个月,采用改良Rankin量表(mRS)评估其预后情况;并运用Pearson相关性分析评估HbA1c水平与NIHSS、mRS评分相关性.结果:研究组患者空腹血糖、HbA1c水平以及NIHSS和mRS评分均高于对照组,差异均有统计学意义(P<0.05).Pearson相关性分析结果显示,急性脑梗死合并2型糖尿病患者HbA1c水平与NIHSS及mRS评分均呈正相关(P<0.05).结论:急性脑梗死合并2型糖尿病患者HbA1c水平与其早期神经功能损伤及短期预后相关,临床实践中应强调优化血糖管理,以改善患者预后.
Objective:To explore the correlation between glycated haemoglobin(HbA1c)levels in patients with acute cerebral infarction combined with type 2 diabetes mellitus and the extent of their early neurological impairment as well as their short-term prognosis.Methods:A total of 244 patients with acute cerebral infarction combined with type 2 diabetes mellitus admitted to our hospital from July 2021 to October 2023 were selected as research subjects.Based on HbA1c levels,they were divided into study group(n=46,HbA1c>8.2%)and control group(n=178,HbA1c≤8.2%).Compare the clinical data and neurological deficits[assessed by the National Institutes of Health stroke scale(NIHSS)]between the two groups,and conduct a 3-month follow-up to evaluate patient outcomes using the modified Rankin scale(mRS),and apply Pearson correlation analysis to assess the correlation between HbA1c levels and NIHSS and mRS scores.Results:The fasting blood glucose,HbA1c levels,NIHSS scores,and mRS scores in study group were all higher than those of control group,with statistically significant differences(P<0.05).Pearson correlation analysis showed that HbA1c levels in patients with acute cerebral infarction combined with type 2 diabetes were positively correlated with both NIHSS and mRS scores(P<0.05).Conclusion:In patients with acute cerebral infarction combined with type 2 diabetes mellitus,HbA1c levels are associated with early neurological impairment and short-term prognosis.Clinical practice should emphasize optimized glycemic control to improve patient outcomes.
作者
邢东辉
王根成
王霞
李佩燕
XING Donghui;WANG Gencheng;WANG Xia;LI Peiyan(The Third Department of Internal Medicine,Shangcai Chongyang Hospital,Zhumadian 463800,China;The First Department of Internal Medicine,Shangcai Chongyang Hospital,Zhumadian 463800,China)
出处
《四川解剖学杂志》
2025年第3期101-103,共3页
Sichuan Journal of Anatomy
关键词
急性脑梗死
2型糖尿病
糖化血红蛋白
短期预后
相关性
Acute cerebral infarction
Type 2 diabetes mellitus
Glycated haemoglobin
Short-term prognosis
Correlation
