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冠脉CTA应用低管电压和低流速、低剂量对比剂模式对图像质量及诊断效能的影响

Effects of coronary CTA with low tube voltage,low flow rate and low-dose contrast agent mode on image quality and diagnostic efficiency
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摘要 目的:观察冠状动脉CT血管造影(CTA)应用低管电压和低流速、低剂量对比剂模式对图像质量及诊断效能的影响。方法:按照随机数字表法将2022年12月-2024年12月本院接受冠脉CTA检查的70例疑似冠状动脉狭窄患者分成2组:观察组(n=35)、对照组(n=35)。其中对照组冠脉CTA检查参数为常规参数(管电压120 KV、流速3.5-5.0 mL·s^(-1)、对比剂为350 mgI·mL^(-1))碘帕醇。观察组则检查时参数设置为低管电压100 kV、低流速3.0-4.0 mL·s^(-1)、对比剂为300 mgI·mL^(-1)碘佛醇(低剂量)。对比两组图像质量;以经导管冠状动脉造影(CAG)为金标准,观察两组冠脉CTA检测用于冠状动脉狭窄疾病的诊断效能。结果:观察组、对照组主动脉根部、S1、S5、S6、S11、S12的图像质量评分数据对比无明显差异(P>0.05);观察组、对照组CTA检查与CAG检查的Kappa检验呈高度一致性(Kappa值=0.799、0.746)。观察组灵敏度、特异度、准确率各为96.55%、83.33%、94.29%,对照组则为96.30%、75.00%、91.43%,两组上述不同数据对比差异无统计学意义(P>0.05)。结论:冠脉CTA应用低管电压和低流速、低剂量对比剂模式对图像质量无明显影响,可确保图像质量,有利于冠状动脉狭窄的检出,诊断效能较高。 Objective:To observe the effects of coronary CT angiography(CTA)with low tube voltage,low flow rate and low-dose contrast agent mode on image quality and diagnostic efficiency.Methods:According to random number table method,70 patients with suspected coronary stenosis who underwent coronary CTA in the hospital were divided into observation group(n=35)and control group(n=35)between December 2022 and December 2024.The parameters setting of coronary CTA in control group and observation group was as follow:(tube voltage:120 kV,flow rate:3.5-5.0 mL·s^(-1),dosage of contrast agent iopamidol:350 mgI·mL^(-1),tube voltage:100 kV,flow rate:3.0-4.0 mL·s^(-1),dosage of iopamidol:300 mgI·mL^(-1)).The images quality in the two groups was compared.Taking transcatheter coronary angiography(CAG)as the golden standard,diagnostic efficiency of coronary CTA for coronary stenosis in the two groups was observed.Results:There was no significant difference in quality scores of coronary segmentation images between the two groups(P>0.05).Kappa test showed that consistency between CTA and CAG was high in observation group and control group(Kappa=0.799,0.746).There was no significant difference in sensitivity,specificity or accuracy between observation group and control group(96.55%,83.33%,94.29%vs 96.30%,75.00%91.43%;P>0.05).Conclusion:Coronary CTA with low tube voltage,low flow rate and low-dose contrast agent mode has no significant effect on images quality,which can ensure image quality and is conducive to the detection of coronary stenosis,with high diagnostic efficiency.
作者 高阳 肖琼 李丽 Gao Yang;Xiao Qiong;Li Li(Imaging Center,Xinyu People's Hospital,Xinyu 338000,Jiangxi,China)
出处 《四川生理科学杂志》 2025年第12期2783-2785,2788,共4页
关键词 冠脉CTA 低流速 低剂量 低管电压 图像质量 诊断效能 Coronary CTA Low flow rate Low dose Low tube voltage Image quality Diagnostic efficiency
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