摘要
目的:探讨内镜下套扎术联合生长抑素治疗肝硬化并发食管胃底静脉曲张破裂出血的疗效。方法:回顾性分析2024年1月—2025年3月厦门市杏林医院收治的100例肝硬化并发食管胃底静脉曲张破裂患者临床资料,根据治疗方式不同分为对照组与观察组各50例。对照组接受内镜下套扎术治疗,观察组在对照组的基础上接受生长抑素治疗,比较两组的临床疗效、胃肠功能、血液指标及止血与住院时间。结果:治疗后观察组临床疗效、空腹胃液pH值、血红蛋白浓度和血小板计数均高于对照组;胃肠功能障碍评分、止血与住院时间均低于对照组。差异有统计学意义(P<0.05)。结论:超早期内镜下止血和生长抑素可以提高急性上消化道患者的治疗效果,改善胃肠功能,提高血红蛋白浓度和血小板计数并减少出血与住院时间。
Objective:To explore the efficacy of endoscopic ligation combined with somatostatin in the treatment of esophageal and gastric variceal bleeding complicated with liver cirrhosis.Method:A retrospective selection was made of 100 patients with liver cirrhosis complicated with esophageal and gastric variceal rupture admitted to Xiamen Xinglin Hospital from January 2024 to March 2025.They were divided into a control group and an observation group,with 50 cases in each group,according to different treatment methods.The control group received endoscopic ligation treatment,while the observation group received somatostatin treatment on the basis of the control group.The clinical efficacy,gastrointestinal function,blood indicators,hemostasis and hospital stay of the two groups were compared.Result:After treatment,the clinical efficacy,fasting gastric juice pH value,hemoglobin concentration and platelet count of the observation group were all higher than those of the control group.The scores of gastrointestinal dysfunction,hemostasis and hospital stay were all lower than those of the control group.The differences were statistically significant(P<0.05).Conclusion:Ultra-early endoscopic hemostasis and somatostatin can enhance the therapeutic effect of patients with acute upper gastrointestinal tract,improve gastrointestinal function,increase hemoglobin concentration and platelet count,and reduce bleeding and hospital stay.
作者
徐炜乾
XU Weiqian(Xiamen Xinglin Hospital,Xiamen 361000,China)
出处
《中外医学研究》
2025年第35期37-40,共4页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
内镜下套扎术
生长抑素
肝硬化
食管胃底静脉曲张
Endoscopic ligation
Growth inhibitor
Cirrhosis
Esophageal and gastric varices
