摘要
目的探究92例多发性骨髓瘤(MM)患者癌因性疲乏现状,分析其与感知控制、希望水平的相关性。方法选择九江市第一人民医院2022年5月-2025年3月收治的92例MM患者,以中文版癌症疲乏量表(CFS)、癌症经验与效能量表(CEES)、Herth希望量表(HHI)分别评估癌因性疲乏、感知控制、希望水平,另统计一般资料,分析影响92例MM患者癌因性疲乏相关因素及其与感知控制、希望水平的相关性。结果92例MM患者CFS评分为(39.14±3.59)分,CEES中癌症经验评分为(45.63±4.20)分,控制效能评分为(41.74±3.87)分,HHI评分为(33.85±3.17)分;Pearson相关性分析显示,癌因性疲乏与感知控制中癌症经验呈正相关(P<0.05);与感知控制中控制效能、希望水平呈负相关(P<0.05);单因素分析显示,不同年龄、病程、血红蛋白水平、化疗频率患者CFS评分比较,有统计学差异(P<0.05);多元线性回归分析结果显示:年龄>60岁、病程≥12个月、血红蛋白水平<90g/L、化疗频率≥4次/周均是影响MM患者癌因性疲乏的危险因素(P<0.05)。结论MM患者癌因性疲乏受年龄、病程、血红蛋白水平、化疗频率影响,且与感知控制、希望水平具有相关性,临床需据此采取干预措施。
Objective To investigate the status of cancer-related fatigue in 92 patients with multiple myeloma(MM)and analyze its correlation with perceived control and hope levels.Methods Ninety-two MM patients admitted to Jiujiang First People’s Hospital from May 2022 to March 2025 were selected.The Chinese version of the Cancer Fatigue Scale(CFS),Cancer Experience and Effectiveness Scale(CEES),and Herth Hope Inventory(HHI)to assess cancer-related fatigue,perceived control,and hope levels,respectively.General demographic data were also collected.The study analyzed factors influencing cancer-related fatigue and its correlations with perceived control and hope levels among these patients.Results The CFS score for 92 MM patients was(39.14±3.59)points,the cancer experience score in CEES was(45.63±4.20)points,the control efficacy score was(41.74±3.87)points,and the HHI score was(33.85±3.17)points.Pearson correlation analysis revealed that cancer-related fatigue positively correlated with cancer experience within perceived control(P<0.05)and negatively correlated with perceived control efficacy and hope level(P<0.05).Univariate analysis demonstrated statistically significant differences in CFS scores among patients with varying ages,disease duration,hemoglobin levels,and chemotherapy frequency(P<0.05).Multivariate linear regression analysis revealed that age>60 years,disease duration≥12 months,hemoglobin level<90 g/L,and chemotherapy frequency≥4 times/week were all risk factors influencing cancer-related fatigue in MM patients(P<0.05).Conclusion Cancer-related fatigue in MM patients is influenced by age,disease duration,hemoglobin levels,and chemotherapy frequency,and correlates with perceived control and hope levels.Clinical interventions should be tailored accordingly.
作者
周玲玲
汪晓燕
李梦颖
刘红霞
Zhou Lingling;Wang Xiaoyan;Li Mengying;Liu Hongxia(Jiujiang First People’s Hospital,Jiujiang,Jiangxi 332000,China)
出处
《首都食品与医药》
2026年第1期126-129,共4页
Capital Food Medicine
关键词
多发性骨髓瘤
癌因性疲乏
感知控制
希望水平
相关性
Multiple myeloma
Cancer-related fatigue
Perceived control
Hope levels
Correlation
