摘要
高尿酸血症是一种常见的代谢性疾病,其典型特征为血清尿酸水平异常升高,发病机制主要涉及嘌呤代谢紊乱或肾脏尿酸排泄功能障碍,还与遗传、年龄、环境等因素有关,与痛风、慢性肾病及心血管疾病也密切相关。目前西医治疗本病虽能有效控制尿酸水平,但长期使用不良反应较明显。中医药在缓解高尿酸血症症状、改善患者体质、降低复发率等方面优势显著。近些年来,对中药复方、单药、有效成分等干预手段的研究不断深入,发现中药可通过抗氧化、抗炎和调节尿酸代谢等机制改善高尿酸血症患者病情及预后。本研究系统梳理了有关中医药治疗高尿酸血症的最新研究进展,旨在进一步探明相关作用机制,为中医药诊疗高尿酸血症提供更有力的依据。
Hyperuricemia is a common metabolic disorder,characterized by abnormally elevated serum uric acid levels.Its pathogenesis mainly involves purine metabolism disorders or renal uric acid excretion dysfunction,and is also related to heredity,age,environmental and other factors.It is closely associated with gout,chronic kidney disease and cardiovascular diseases.At present,although Western medicine can effectively control uric acid levels in the treatment of this disease,the adverse reactions are relatively obvious after long-term medication.Traditional Chinese medicine has significant advantages in alleviating the symptoms of hyperuricemia,improving patients'physical condition,and decreasing the recurrence rate.In recent years,research on intervention methods such as traditional Chinese medicine compound prescriptions,single Chinese medicinal material,and active ingredients has been continuously deepened,and it has been found that Chinese medicinal material improves the condition and prognosis of patients with hyperuricemia through mechanisms such as antioxidation,anti-inflammation,and regulation of uric acid metabolism.In this study,the latest research progress on the treatment of hyperuricemia in traditional Chinese medicine is systematically reviewed,aiming to further clarify the relevant action mechanism,so as to provide a more powerful basis for the diagnosis and treatment of hyperuricemia in traditional Chinese medicine.
出处
《中医临床研究》
2025年第27期126-131,共6页
Clinical Journal Of Chinese Medicine
基金
新疆维吾尔自治区自然科学基金(2024D01A35):探讨脊蓉益肾方对糖尿病肾病大鼠肾脏内质网应激水平的机制研究
新疆维吾尔自治区重点研发任务专项(2024B03034-1):“西北燥证”相关疾病专病数据库及循证研究证据体系构建。
关键词
高尿酸血症
代谢性疾病
中医药
针灸
研究进展
Hyperuricemia
Metabolic disease
Traditional Chinese medicine
Acupuncture
Research progress
