摘要
本综述阐述了毒理学关注阈值(TTC)方法在植物提取物用于化妆品安全评估中的应用。深入剖析了TTC方法的原理、适用范围,以及在植物提取物安全评估中的具体实施步骤、关键因素与注意事项,揭示了TTC方法在评估植物提取物安全性方面的优势与局限性,为化妆品行业中植物提取物的安全使用提供科学、可靠的理论依据和实践指导,推动化妆品安全评估技术的发展完善,促进化妆品行业健康可持续发展。
This review article explores the application of the toxicological threshold of concern(TTC)methodology in the safety evaluation of plant extracts commonly used in cosmetic formulations.It expounds on the foundational principles of the TTC approach,its range of applicability,and the detailed steps involved in its implementation.Additionally,the review addresses the critical factors and precautions essential to the assessment of plant extract safety.Through highlighting the advantages and constraints of the TTC method,the article reveals its efficacy in ensuring the safety of plant extracts in cosmetics.It provides a solid theoretical framework and practical insights for the safe utilization of these extracts in the cosmetic industry.Furthermore,the review contributes to the advancement and enhancement of cosmetic safety assessment techniques,driving the industry towards healthier and more sustainable development.
作者
陈永春
夏少辉
朱洁
陈志雄
CHEN Yongchun;XIA Shaohui;ZHU Jie;CHEN Zhixiong(Nanjing Yadong Network Technology Co.,Ltd.,Nanjing 210000,China;Huzhou Jiaheng Industrial Co.,Ltd.,Huzhou 313000,China)
出处
《中国野生植物资源》
2025年第11期83-88,共6页
Chinese Wild Plant Resources
关键词
毒理学关注阈值
安全评估
植物提取物
Threshold of toxicological concern
Safety assessment
Plant extracts