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静电纺不对称湿润性Janus膜在伤口敷料中的研究进展

Research Progress of Electrospun Asymmetric Wetting Janus Membrane in Wound Dressings
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摘要 人们常会因为外界环境或自身疾病等原因,使皮肤出现伤口,若是对伤口处理不当,就会大大延长伤口修复的时间,甚至会造成伤口感染恶化,给患者带来极大的痛苦。因此,人们常用伤口敷料辅助皮肤进行快速、有效修复。介绍了静电纺丝的原理、特点及应用,传统纳米纤维膜敷料常通过添加药物提升促伤口修复性能。针对普通伤口敷料单一润湿性能的局限性,阐述了利用静电纺丝技术制备不对称湿润性Janus膜伤口敷料的优点和导液机理,重点综述了单层和多层不对称湿润性Janus膜伤口敷料的制备方法和应用,指出具有静电纺不对称润湿性的Janus膜,可调控性强,能灵活适应不同伤口敷料的需求,具有广阔的应用前景。 Wounds on the skin often occur due to external environmental factors or personal illnesses.Improper wound management can significantly prolong the healing process and even lead to infection and deterioration,causing great pain to patients.Therefore,wound dressings are commonly used to assist in rapid and effective skin repair.The principle,characteristics,and applications of electrospinning were introduced.Traditional nanofiber membrane dressings often enhanced their wound-healing promotion performance by incorporating drugs.Normal wound dressings possess unique wettability,thus the advantage and fluid-conducting mechanism of electrospun asymmetric wetting Janus membranes were stated.The preparation method and application of monolayer and multilayer electrospun asymmetric wetting Janus membranes were summarized.Electrospun asymmetric wetting Janus membranes with controllable asymmetric wettability can meet the needs of different wound dressings,and possess broad application application prospects.
作者 黄沛良 何明 黄雪 张步宁 丁姣 尹国强 Huang Peiliang;He Ming;Huang Xue;Zhang Bunin;Ding Jiao;Yin Guoqiang(College of Chemistry and Chemical Engineering,Zhongkai University of Agriculture and Engineering,Guangzhou 510225,China;Institute of Green Materials and Energy Technology,Guangzhou Vocational University of Science and Technology,Guangzhou 510550,China)
出处 《广东化工》 2025年第22期73-76,45,共5页 Guangdong Chemical Industry
基金 广东省普通高校重点领域专项(2023ZDZX4022) 广东省教育厅-青年创新人才项目(2018KQNCX116) 仲恺农业工程学院研究生科技创新项目(KA25YY16734)。
关键词 伤口敷料 生物医学工程 静电纺丝 Janus膜 复合材料 纳米材料 wound dressing biomedical engineering electrospinning Janus membrane composites nanomaterials
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