摘要
糖尿病周围神经病变(diabetes peripheral neuropathy,DPN)作为糖尿病常见慢性并发症,发病率高,早期诊断和治疗至关重要。MRI凭借软组织分辨率高、无创、多参数、多方位成像优势,在DPN早期诊断、发病机制探究、疗效监测等方面展现出巨大潜力,有望成为可靠的定量评估方法。本文主要基于结构和功能MRI等技术,对DPN不同亚型的中枢改变差异进行了综述,指出了当前研究的局限性并指出了今后研究的方向,以期为临床诊疗提供线索。
Diabetic peripheral neuropathy(DPN),as a common chronic complication of diabetes,has a high incidence.Early diagnosis and treatment are essential.With the advantages of high soft tissue resolution,non-invasive,multi-parameter,and multi-directional imaging,MRI technology has shown great potential in early diagnosis,pathogenesis exploration,and efficacy monitoring of DPN,and is expected to become a reliable quantitative evaluation method.This article is mainly based on structural and functional magnetic resonance imaging and other technologies,it provides a review of the differences in central nervous system changes among different subtypes of DPN,and identifies current research limitations,points out future study directions,and aims to offer clues for clinical diagnosis and treatment.
作者
谷丛丛
吕亚楠
姜兴岳
GU Congcong;LÜYanan;JIANG Xingyue(Department of Radiology,Affiliated Hospital of Binzhou Medical College,Binzhou 256603,China)
出处
《磁共振成像》
北大核心
2025年第11期190-195,202,共7页
Chinese Journal of Magnetic Resonance Imaging
基金
山东省自然科学基金项目(编号:ZR2022MH118)。
关键词
糖尿病周围神经病变
磁共振成像
结构磁共振成像
功能磁共振成像
磁共振波谱成像
磁共振灌注成像
diabetic peripheral neuropathy
magnetic resonance imaging
structural magnetic resonance imaging
functional magnetic resonance imaging
magnetic resonance spectroscopic imaging
perfusion-weighted imaging
