摘要
目的系统分析颅内动脉瘤患者植入不同材质血流导向密网支架(Flow Diverter,FD)的围手术期安全性和手术效率,为临床选择更安全且有效的治疗方式提供实证依据。方法本研究为单中心回顾性研究,选取2022年1月1日至2025年3月31日间使用FD治疗的1316例患者为研究对象。根据植入密FD质将入组的患者分为镍钛合金组(118例)和钴铬合金组(1198例),并对以下核心指标进行比较分析:手术时间、术中出血量、术后住院日、术后抗炎/抗水肿用药次数以及FD、支撑导管、微导管、微导丝的使用数量。结果钴铬合金组在术后住院日和手术时间方面显著优于镍钛合金组,且差异有统计学意义(P<0.05);在术中出血量及抗炎/抗水肿用药次数方面,2组差异无统计学意义(P>0.05)。在微导管的使用数量方面,镍钛合金组显著低于钴铬合金组,差异有统计学意义(P<0.05),此外,钴铬合金组使用数量逐年增加,而镍钛合金组的使用占比显著下降。结论钴铬合金FD在手术效率和患者恢复速度方面优于镍钛合金FD,在手术创伤和术后炎症控制方面两者无差异。本研究可为临床选择更安全有效的FD提供参考依据。
Objective To systematically analyze the perioperative safety and surgical efficiency of implanting flow diverters(FD)of different materials in patients with intracranial aneurysms,and to provide empirical evidence for the clinical selection of safer and more effective treatment methods.Methods This study was a single-center retrospective study.A total of 1316 patients who were treated with FD from January 1,2022 to March 31,2025 were selected as the research subjects.The enrolled patients were divided into the nickel-titanium alloy group(118 cases)and the cobalt-chromium alloy group(1198 cases)based on the implantation of FD.The following core indicators were compared and analyzed:operation time,intraoperative blood loss,postoperative hospital stay,the frequency of postoperative anti-inflammatory/anti-edema medication,and the usage quantities of FDS,support catheters,microcatheters,and microguidewires.Results The cobalt-chromium alloy group was significantly superior to the nickel-titanium alloy group in terms of postoperative hospital stay and operation time,and the differences were statistically significant(P<0.05).However,there was no statistically significant difference between the two groups in terms of intraoperative blood loss and the frequency of anti-inflammatory/anti-edema medication(P>0.05).In terms of the number of microcatheters used,the nitinol group was significantly lower than the cobalt-chromium alloy group,and the difference was statistically significant(P<0.05).Additionally,the number of microcatheters used in the cobalt-chromium alloy group increased year by year,while the proportion used in the nickel-titanium alloy group decreased significantly.Conclusion Cobalt-chromium alloy FD is superior to nickel-titanium alloy FD in terms of surgical efficiency and patient recovery speed,while there is no difference between the two in terms of surgical trauma and postoperative inflammation control.This study can provide a basis for the clinical selection of safer and more effective FD.
作者
程佳佳
李东
荣瑶
吴萍
黄跃
胡鹏
吴航
CHENG Jiajia;LI Dong;RONG Yao;WU Ping;HUANG Yue;HU Peng;WU Hang(Department of Medical Engineering,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;Information Center,Xuanwu Hospital,Capital Medical University,Beijing 100053,China;Department of Neurosurgery,Xuanwu Hospital,Capital Medical University,Beijing 100053,China)
出处
《中国医疗设备》
2025年第12期25-30,41,共7页
China Medical Devices
基金
《中国医疗设备》杂志社课题(2025-CMDKT-01-001)。
