摘要
目的梳理和归纳辽宁中医药大学附属医院中医经典病房的痰瘀痹阻型痛风性关节炎合并动脉粥样硬化患者临床常用药物,总结出用药规律,为中医药治疗该种复合症候群提供了一定的临床参考价值。方法选择2023年1月—2023年12月在辽宁中医药大学附属医院中医经典病房明确诊断为痰瘀痹阻型痛风性关节炎合并动脉粥样硬化的住院患者处方作为研究对象,用Excel软件、中医传承辅助平台V3.0等方法对其相关数据进行整理及统计学分析。结果共纳入患者83例,收集中药处方83张,使用中药130味,总用药次数为1121次,其中有20种药物用药次数超过20次为高频次中药,四气以平性、温性、寒性为主,五味以甘、苦、辛味为主。高频药物聚类分析得到6组聚类,功效主要体现为活血化瘀、清热利湿、通利关节。核心药物网络分析共得出12味中药,分别为苍术、茯苓、薏苡仁、黄柏、黄芩、丹参、土茯苓、当归、木瓜、泽泻、牛膝、甘草。结论对于治疗痰瘀痹阻型痛风性关节炎合并动脉粥样硬化的患者,常采用活血化瘀与清热利湿,佐以补虚的治法。
Objective This study classified and summarized the commonly used clinical drugs for patients with osteoarthritis and atherosclerosis,providing certain clinical references for the treatment of this complex syndrome in traditional Chinese medicine.Methods In this study,the prescriptions of inpatients diagnosed with phlegm stasis obstructive gouty arthritis and atherosclerosis in the classic ward of traditional Chinese medicine of the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from January 2023 to December 2023 were selected as the research objects,and the relevant data were sorted out and statistically analyzed by Excel software and traditional Chinese medicine inheritance assistance platform V3.0.Results The study included data from 83 patients,with 83 traditional Chinese medicine(TCM)prescriptions collected.A total of 130 types of medicinal substances were used,with an overall usage frequency of 1,121 instances.Among them,20 types of medicines were used more than 20 times and are classified as high-frequency drugs.Medicines with neutral,warm,and cold thermal properties predominated,while in terms of taste characteristics,sweet,bitter,and pungent flavors were most common.Cluster analysis of the high-frequency medicines identified six cluster groups,whose main effects include:promoting blood circulation and removing blood stasis,clearing heat and draining dampness,and alleviating joint pain.Network analysis of the core medicines revealed 12 types of Chinese medicinal substances,namely:Cangzhu,Fuling,Yiyiren,Huangbai,Huangqin,Danshen,Tufuling,Danggui,Muxiang,Zexie,Niuxi,and Gancao.ConclusionFor the treatment of patients with combined atherosclerosis and sputum palsy obstructive gothic arthritis,blood-activating and pure heat dampness are usually used,supplemented by supplementary therapy.
作者
仇真
汲泓
QIU Zhen;JI Hong(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;Shengjing Hospital,China Medical University,Shenyang 110000,Liaoning,China)
出处
《实用中医内科杂志》
2025年第9期76-79,I0012,I0013,共6页
Journal of Practical Traditional Chinese Internal Medicine
基金
辽宁省自然科学基金项目(201602480)。
